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Phospholipase D as a therapeutic target in brain disorders.
Lindsley CW, Brown HA. Lindsley CW, et al. Among authors: brown ha. Neuropsychopharmacology. 2012 Jan;37(1):301-2. doi: 10.1038/npp.2011.178. Neuropsychopharmacology. 2012. PMID: 22157867 Free PMC article. No abstract available.
Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells.
O'Reilly MC, Scott SA, Brown KA, Oguin TH 3rd, Thomas PG, Daniels JS, Morrison R, Brown HA, Lindsley CW. O'Reilly MC, et al. Among authors: brown ha, brown ka. J Med Chem. 2013 Mar 28;56(6):2695-9. doi: 10.1021/jm301782e. Epub 2013 Mar 13. J Med Chem. 2013. PMID: 23445448 Free PMC article.
Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity.
Lewis JA, Scott SA, Lavieri R, Buck JR, Selvy PE, Stoops SL, Armstrong MD, Brown HA, Lindsley CW. Lewis JA, et al. Among authors: brown ha. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1916-20. doi: 10.1016/j.bmcl.2009.02.057. Epub 2009 Feb 20. Bioorg Med Chem Lett. 2009. PMID: 19268584 Free PMC article.
261 results