Kleinjans JC - Search Results

1

Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells.

Theunissen PT, Pennings JL, Robinson JF, Claessen SM, Kleinjans JC, Piersma AH. Theunissen PT, et al. Among authors: kleinjans jc. Toxicol Sci. 2011 Aug;122(2):437-47. doi: 10.1093/toxsci/kfr134. Epub 2011 May 25. Toxicol Sci. 2011. PMID: 21613230

2

Evaluation of developmental toxicant identification using gene expression profiling in embryonic stem cell differentiation cultures.

van Dartel DA, Pennings JL, de la Fonteyne LJ, Brauers KJ, Claessen S, van Delft JH, Kleinjans JC, Piersma AH. van Dartel DA, et al. Among authors: kleinjans jc. Toxicol Sci. 2011 Jan;119(1):126-34. doi: 10.1093/toxsci/kfq291. Epub 2010 Oct 8. Toxicol Sci. 2011. PMID: 20935163

3

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures.

van Dartel DA, Pennings JL, de la Fonteyne LJ, Brauers KJ, Claessen S, van Delft JH, Kleinjans JC, Piersma AH. van Dartel DA, et al. Among authors: kleinjans jc. Toxicol Appl Pharmacol. 2011 Mar 1;251(2):110-8. doi: 10.1016/j.taap.2010.12.008. Epub 2010 Dec 28. Toxicol Appl Pharmacol. 2011. PMID: 21192963

4

Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test.

van Dartel DA, Pennings JL, Robinson JF, Kleinjans JC, Piersma AH. van Dartel DA, et al. Among authors: kleinjans jc. Toxicol Lett. 2011 Mar 5;201(2):143-51. doi: 10.1016/j.toxlet.2010.12.019. Epub 2010 Dec 30. Toxicol Lett. 2011. PMID: 21195148

5

Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.

van Kesteren PC, Zwart PE, Pennings JL, Gottschalk WH, Kleinjans JC, van Delft JH, van Steeg H, Luijten M. van Kesteren PC, et al. Among authors: kleinjans jc. Toxicol Sci. 2011 Sep;123(1):123-32. doi: 10.1093/toxsci/kfr169. Epub 2011 Jun 29. Toxicol Sci. 2011. PMID: 21715664

6

Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).

Theunissen PT, Robinson JF, Pennings JL, de Jong E, Claessen SM, Kleinjans JC, Piersma AH. Theunissen PT, et al. Among authors: kleinjans jc. Toxicol Sci. 2012 Feb;125(2):430-8. doi: 10.1093/toxsci/kfr293. Epub 2011 Nov 1. Toxicol Sci. 2012. PMID: 22045034

7

Complementary detection of embryotoxic properties of substances in the neural and cardiac embryonic stem cell tests.

Theunissen PT, Pennings JL, van Dartel DA, Robinson JF, Kleinjans JC, Piersma AH. Theunissen PT, et al. Among authors: kleinjans jc. Toxicol Sci. 2013 Mar;132(1):118-30. doi: 10.1093/toxsci/kfs333. Epub 2012 Dec 13. Toxicol Sci. 2013. PMID: 23243006

8

Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).

Theunissen PT, Robinson JF, Pennings JL, van Herwijnen MH, Kleinjans JC, Piersma AH. Theunissen PT, et al. Among authors: kleinjans jc. Toxicol Appl Pharmacol. 2012 Aug 1;262(3):330-40. doi: 10.1016/j.taap.2012.05.011. Epub 2012 May 23. Toxicol Appl Pharmacol. 2012. PMID: 22634333

9

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene.

van Delft J, Gaj S, Lienhard M, Albrecht MW, Kirpiy A, Brauers K, Claessen S, Lizarraga D, Lehrach H, Herwig R, Kleinjans J. van Delft J, et al. Toxicol Sci. 2012 Dec;130(2):427-39. doi: 10.1093/toxsci/kfs250. Epub 2012 Aug 13. Toxicol Sci. 2012. PMID: 22889811

10

Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma.

Rieswijk L, Claessen SM, Bekers O, van Herwijnen M, Theunissen DH, Jennen DG, de Kok TM, Kleinjans JC, van Breda SG. Rieswijk L, et al. Among authors: kleinjans jc. Toxicology. 2016 Mar 28;350-352:31-9. doi: 10.1016/j.tox.2016.05.002. Epub 2016 May 3. Toxicology. 2016. PMID: 27153756

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