Li J - Search Results

1

Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases?

Deng J, Feng E, Ma S, Zhang Y, Liu X, Li H, Huang H, Zhu J, Zhu W, Shen X, Miao L, Liu H, Jiang H, Li J. Deng J, et al. Among authors: li j, li h. J Med Chem. 2011 Jul 14;54(13):4508-22. doi: 10.1021/jm200161c. Epub 2011 Jun 7. J Med Chem. 2011. PMID: 21615130

2

Rationale, design, and synthesis of novel phenyl imidazoles as opioid receptor agonists for gastrointestinal disorders.

Breslin HJ, Miskowski TA, Rafferty BM, Coutinho SV, Palmer JM, Wallace NH, Schneider CR, Kimball ES, Zhang SP, Li J, Colburn RW, Stone DJ, Martinez RP, He W. Breslin HJ, et al. Among authors: li j. J Med Chem. 2004 Oct 7;47(21):5009-20. doi: 10.1021/jm030548r. J Med Chem. 2004. PMID: 15456245

3

Novel indolylindazolylmaleimides as inhibitors of protein kinase C-beta: synthesis, biological activity, and cardiovascular safety.

Zhang HC, Derian CK, McComsey DF, White KB, Ye H, Hecker LR, Li J, Addo MF, Croll D, Eckardt AJ, Smith CE, Li Q, Cheung WM, Conway BR, Emanuel S, Demarest KT, Andrade-Gordon P, Damiano BP, Maryanoff BE. Zhang HC, et al. Among authors: li j, li q. J Med Chem. 2005 Mar 24;48(6):1725-8. doi: 10.1021/jm049478u. J Med Chem. 2005. PMID: 15771419

4

In vitro pharmacological characterization of TKI-28, a broad-spectrum tyrosine kinase inhibitor with anti-tumor and anti-angiogenic effects.

Guo XN, Zhong L, Tan JZ, Li J, Luo XM, Jiang HL, Nan FJ, Lin LP, Zhang XW, Ding J. Guo XN, et al. Among authors: li j. Cancer Biol Ther. 2005 Oct;4(10):1125-32. doi: 10.4161/cbt.4.10.2024. Epub 2005 Oct 15. Cancer Biol Ther. 2005. PMID: 16096368 Free article.

5

Discovering novel chemical inhibitors of human cyclophilin A: virtual screening, synthesis, and bioassay.

Li J, Chen J, Gui C, Zhang L, Qin Y, Xu Q, Zhang J, Liu H, Shen X, Jiang H. Li J, et al. Bioorg Med Chem. 2006 Apr 1;14(7):2209-24. doi: 10.1016/j.bmc.2005.11.006. Epub 2005 Nov 22. Bioorg Med Chem. 2006. PMID: 16307882 Free PMC article.

6

Strategy for discovering chemical inhibitors of human cyclophilin a: focused library design, virtual screening, chemical synthesis and bioassay.

Li J, Zhang J, Chen J, Luo X, Zhu W, Shen J, Liu H, Shen X, Jiang H. Li J, et al. J Comb Chem. 2006 May-Jun;8(3):326-37. doi: 10.1021/cc0501561. J Comb Chem. 2006. PMID: 16677001

7

One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation.

Li J, Chen J, Zhang L, Wang F, Gui C, Zhang L, Qin Y, Xu Q, Liu H, Nan F, Shen J, Bai D, Chen K, Shen X, Jiang H. Li J, et al. Bioorg Med Chem. 2006 Aug 15;14(16):5527-34. doi: 10.1016/j.bmc.2006.04.026. Epub 2006 May 6. Bioorg Med Chem. 2006. PMID: 16682211 Free PMC article.

8

Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.

Li J, Zheng M, Tang W, He PL, Zhu W, Li T, Zuo JP, Liu H, Jiang H. Li J, et al. Among authors: li t. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5009-13. doi: 10.1016/j.bmcl.2006.07.047. Epub 2006 Jul 28. Bioorg Med Chem Lett. 2006. PMID: 16876409

9

Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives.

Li J, Tan JZ, Chen LL, Zhang J, Shen X, Mei CL, Fu LL, Lin LP, Ding J, Xiong B, Xiong XS, Liu H, Luo XM, Jiang HL. Li J, et al. Acta Pharmacol Sin. 2006 Sep;27(9):1259-71. doi: 10.1111/j.1745-7254.2006.00437.x. Acta Pharmacol Sin. 2006. PMID: 16923349

10

Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features.

Chen L, Li J, Luo C, Liu H, Xu W, Chen G, Liew OW, Zhu W, Puah CM, Shen X, Jiang H. Chen L, et al. Among authors: li j. Bioorg Med Chem. 2006 Dec 15;14(24):8295-306. doi: 10.1016/j.bmc.2006.09.014. Epub 2006 Oct 12. Bioorg Med Chem. 2006. PMID: 17046271 Free PMC article.

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