Miao L - Search Results

1

Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases?

Deng J, Feng E, Ma S, Zhang Y, Liu X, Li H, Huang H, Zhu J, Zhu W, Shen X, Miao L, Liu H, Jiang H, Li J. Deng J, et al. Among authors: miao l. J Med Chem. 2011 Jul 14;54(13):4508-22. doi: 10.1021/jm200161c. Epub 2011 Jun 7. J Med Chem. 2011. PMID: 21615130

2

The effect of first-in-class small molecule RhoA inhibitor, HL07, on the phenylephrine-induced artery contraction.

Zhang Y, Deng J, Ma S, Xue L, Zhu J, Zhu WL, Jiang HL, Li J, Miao LY. Zhang Y, et al. Among authors: miao ly. Curr Pharm Des. 2012;18(27):4258-64. doi: 10.2174/138161212802430387. Curr Pharm Des. 2012. PMID: 22621254

3

Development of second-generation small-molecule RhoA inhibitors with enhanced water solubility, tissue potency, and significant in vivo efficacy.

Ma S, Deng J, Li B, Li X, Yan Z, Zhu J, Chen G, Wang Z, Jiang H, Miao L, Li J. Ma S, et al. Among authors: miao l. ChemMedChem. 2015 Jan;10(1):193-206. doi: 10.1002/cmdc.201402386. Epub 2014 Nov 5. ChemMedChem. 2015. PMID: 25377276

4

Discovery of benzylidene derivatives as potent Syk inhibitors: synthesis, SAR analysis, and biological evaluation.

Zhang L, Liu W, Mao F, Zhu J, Dong G, Jiang H, Sheng C, Miao L, Huang L, Li J. Zhang L, et al. Among authors: miao l. Arch Pharm (Weinheim). 2015 Jul;348(7):463-74. doi: 10.1002/ardp.201500096. Epub 2015 Jun 1. Arch Pharm (Weinheim). 2015. PMID: 26032727

5

The structure of a small GTPaseRhoA in complex with PDZRhoGEF and the inhibitor HL47.

Yan Z, Ma S, Zhang Y, Ma L, Wang F, Li J, Miao L. Yan Z, et al. Among authors: miao l. Biotechnol Lett. 2017 May;39(5):745-750. doi: 10.1007/s10529-017-2292-7. Epub 2017 Feb 1. Biotechnol Lett. 2017. PMID: 28150077

6

Evaluation of the in vitro Chemosensitivity and Correlation with Clinical Outcomes in Lung Cancer using the ATP-TCA.

Chen Z, Zhang S, Ma S, Li C, Xu C, Shen Y, Zhao J, Miao L. Chen Z, et al. Among authors: miao l. Anticancer Agents Med Chem. 2018;18(1):139-145. doi: 10.2174/1871520617666170419123713. Anticancer Agents Med Chem. 2018. PMID: 28425853

7

Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein.

Meng J, Liu XY, Ma S, Zhang H, Yu SD, Zhang YF, Chen MX, Zhu XY, Liu Y, Yi L, Ding XL, Chen XY, Miao LY, Zhong DF. Meng J, et al. Among authors: miao ly. Acta Pharmacol Sin. 2019 Jul;40(7):980-988. doi: 10.1038/s41401-018-0176-6. Epub 2018 Oct 31. Acta Pharmacol Sin. 2019. PMID: 30382184 Free PMC article.

8

Absorption, Metabolism and Excretion of Surufatinib in Rats and Humans.

Li K, Ma S, Miao L, Fan S, Pan B, Zhang W, Su W, Xiong Y, Gu Z, Guo L, Sai Y. Li K, et al. Among authors: miao l. Curr Drug Metab. 2020;21(5):357-367. doi: 10.2174/1389200221666200514131721. Curr Drug Metab. 2020. PMID: 32407271 Clinical Trial.

9

Pharmacokinetics, mass balance, and metabolism of [¹⁴C]vicagrel, a novel irreversible P2Y₁₂ inhibitor in humans.

Zheng YD, Zhang H, Zhan Y, Bian YC, Ma S, Gan HX, Lai XJ, Liu YQ, Gong YC, Liu XF, Sun HB, Li YG, Zhong DF, Miao LY, Diao XX. Zheng YD, et al. Acta Pharmacol Sin. 2021 Sep;42(9):1535-1546. doi: 10.1038/s41401-020-00547-7. Epub 2020 Nov 26. Acta Pharmacol Sin. 2021. PMID: 33244163 Free PMC article.

10

Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP-ribose) polymerase inhibitor, in subjects with advanced solid cancers.

Bian Y, Meng J, Ma S, Li G, Wang Y, Li S, Liu L, Huang C, Zhang H, Zhong D, Miao L. Bian Y, et al. Among authors: miao l. Br J Clin Pharmacol. 2022 Jul;88(7):3307-3320. doi: 10.1111/bcp.15256. Epub 2022 Feb 28. Br J Clin Pharmacol. 2022. PMID: 35112382 Free article. Clinical Trial.

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