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An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli.
Porter CK, Riddle MS, Alcala AN, Sack DA, Harro C, Chakraborty S, Gutierrez RL, Savarino SJ, Darsley M, McKenzie R, DeNearing B, Steinsland H, Tribble DR, Bourgeois AL. Porter CK, et al. Among authors: savarino sj. PLoS One. 2016 Mar 3;11(3):e0149358. doi: 10.1371/journal.pone.0149358. eCollection 2016. PLoS One. 2016. PMID: 26938983 Free PMC article.
Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial.
Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Cantrell JA, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL. Savarino SJ, et al. J Infect Dis. 2017 Jul 1;216(1):7-13. doi: 10.1093/infdis/jix144. J Infect Dis. 2017. PMID: 28541500 Clinical Trial.
Enterotoxigenic E. coli virulence gene regulation in human infections.
Crofts AA, Giovanetti SM, Rubin EJ, Poly FM, Gutiérrez RL, Talaat KR, Porter CK, Riddle MS, DeNearing B, Brubaker J, Maciel M Jr, Alcala AN, Chakraborty S, Prouty MG, Savarino SJ, Davies BW, Trent MS. Crofts AA, et al. Among authors: savarino sj. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8968-E8976. doi: 10.1073/pnas.1808982115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30126994 Free PMC article. Clinical Trial.
Hyperimmune Bovine Colostral Anti-CS17 Antibodies Protect Against Enterotoxigenic Escherichia coli Diarrhea in a Randomized, Doubled-Blind, Placebo-Controlled Human Infection Model.
Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL. Savarino SJ, et al. J Infect Dis. 2019 Jul 2;220(3):505-513. doi: 10.1093/infdis/jiz135. J Infect Dis. 2019. PMID: 30897198 Clinical Trial.
A first in human clinical trial assessing the safety and immunogenicity of transcutaneously delivered enterotoxigenic Escherichia coli fimbrial tip adhesin with heat-labile enterotoxin with mutation R192G.
Riddle MS, Maciel M Jr, Porter CK, Poole ST, Gutierrez RL, Gormley R, Laird RM, Sebeny PJ, Dori KE, Greenleaf ME, Hoq F, Turiansky GW, Jarell A, Hawk D, Tribble D, Savarino SJ. Riddle MS, et al. Among authors: savarino sj. Vaccine. 2020 Oct 21;38(45):7040-7048. doi: 10.1016/j.vaccine.2020.09.025. Epub 2020 Sep 22. Vaccine. 2020. PMID: 32978003
103 results