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A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias.
Olesen MS, Jensen NF, Holst AG, Nielsen JB, Tfelt-Hansen J, Jespersen T, Sajadieh A, Haunsø S, Lund JT, Calloe K, Schmitt N, Svendsen JH. Olesen MS, et al. Among authors: jespersen t. Can J Cardiol. 2011 Jul-Aug;27(4):523.e17-23. doi: 10.1016/j.cjca.2011.01.003. Epub 2011 May 28. Can J Cardiol. 2011. PMID: 21621375 English, French.
KCNQ1 channels sense small changes in cell volume.
Grunnet M, Jespersen T, MacAulay N, Jørgensen NK, Schmitt N, Pongs O, Olesen SP, Klaerke DA. Grunnet M, et al. Among authors: jespersen t. J Physiol. 2003 Jun 1;549(Pt 2):419-27. doi: 10.1113/jphysiol.2003.038455. Epub 2003 Apr 17. J Physiol. 2003. PMID: 12702742 Free PMC article.
242 results