Koeplinger K - Search Results

1

Antiviral efficacy upon administration of a HepDirect prodrug of 2'-C-methylcytidine to hepatitis C virus-infected chimpanzees.

Carroll SS, Koeplinger K, Vavrek M, Zhang NR, Handt L, MacCoss M, Olsen DB, Reddy KR, Sun Z, van Poelje PD, Fujitaki JM, Boyer SH, Linemeyer DL, Hecker SJ, Erion MD. Carroll SS, et al. Among authors: koeplinger k. Antimicrob Agents Chemother. 2011 Aug;55(8):3854-60. doi: 10.1128/AAC.01152-10. Epub 2011 May 31. Antimicrob Agents Chemother. 2011. PMID: 21628542 Free PMC article.

2

Robust antiviral efficacy upon administration of a nucleoside analog to hepatitis C virus-infected chimpanzees.

Carroll SS, Ludmerer S, Handt L, Koeplinger K, Zhang NR, Graham D, Davies ME, MacCoss M, Hazuda D, Olsen DB. Carroll SS, et al. Among authors: koeplinger k. Antimicrob Agents Chemother. 2009 Mar;53(3):926-34. doi: 10.1128/AAC.01032-08. Epub 2008 Dec 15. Antimicrob Agents Chemother. 2009. PMID: 19075052 Free PMC article.

3

Sustained viral response in a hepatitis C virus-infected chimpanzee via a combination of direct-acting antiviral agents.

Olsen DB, Davies ME, Handt L, Koeplinger K, Zhang NR, Ludmerer SW, Graham D, Liverton N, MacCoss M, Hazuda D, Carroll SS. Olsen DB, et al. Among authors: koeplinger k. Antimicrob Agents Chemother. 2011 Feb;55(2):937-9. doi: 10.1128/AAC.00990-10. Epub 2010 Nov 29. Antimicrob Agents Chemother. 2011. PMID: 21115793 Free PMC article.

4

Liver-targeted prodrugs of 2'-C-methyladenosine for therapy of hepatitis C virus infection.

Hecker SJ, Reddy KR, van Poelje PD, Sun Z, Huang W, Varkhedkar V, Reddy MV, Fujitaki JM, Olsen DB, Koeplinger KA, Boyer SH, Linemeyer DL, MacCoss M, Erion MD. Hecker SJ, et al. Among authors: koeplinger ka. J Med Chem. 2007 Aug 9;50(16):3891-6. doi: 10.1021/jm0701021. Epub 2007 Jul 18. J Med Chem. 2007. PMID: 17636948

5

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.

Murgolo N, Therien AG, Howell B, Klein D, Koeplinger K, Lieberman LA, Adam GC, Flynn J, McKenna P, Swaminathan G, Hazuda DJ, Olsen DB. Murgolo N, et al. Among authors: koeplinger k. PLoS Pathog. 2021 Feb 17;17(2):e1009225. doi: 10.1371/journal.ppat.1009225. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33596266 Free PMC article. Review.

6

Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing.

He X, Quan S, Xu M, Rodriguez S, Goh SL, Wei J, Fridman A, Koeplinger KA, Carroll SS, Grobler JA, Espeseth AS, Olsen DB, Hazuda DJ, Wang D. He X, et al. Among authors: koeplinger ka. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2025866118. doi: 10.1073/pnas.2025866118. Proc Natl Acad Sci U S A. 2021. PMID: 33766889 Free PMC article.

7

Liquid microjunction surface sampling probe electrospray mass spectrometry for detection of drugs and metabolites in thin tissue sections.

Van Berkel GJ, Kertesz V, Koeplinger KA, Vavrek M, Kong AN. Van Berkel GJ, et al. J Mass Spectrom. 2008 Apr;43(4):500-8. doi: 10.1002/jms.1340. J Mass Spectrom. 2008. PMID: 18035855

8

Cyclic phosphoramidates as prodrugs of 2'-C-methylcytidine.

Meppen M, Pacini B, Bazzo R, Koch U, Leone JF, Koeplinger KA, Rowley M, Altamura S, Di Marco A, Fiore F, Giuliano C, Gonzalez-Paz O, Laufer R, Pucci V, Narjes F, Gardelli C. Meppen M, et al. Eur J Med Chem. 2009 Sep;44(9):3765-70. doi: 10.1016/j.ejmech.2009.04.043. Epub 2009 May 8. Eur J Med Chem. 2009. PMID: 19493593

9

Comparison of drug distribution images from whole-body thin tissue sections obtained using desorption electrospray ionization tandem mass spectrometry and autoradiography.

Kertesz V, Van Berkel GJ, Vavrek M, Koeplinger KA, Schneider BB, Covey TR. Kertesz V, et al. Anal Chem. 2008 Jul 1;80(13):5168-77. doi: 10.1021/ac800546a. Epub 2008 May 16. Anal Chem. 2008. PMID: 18481874

10

Quantitation of physiological and biochemical barriers to siRNA liver delivery via lipid nanoparticle platform.

Xu Y, Ou M, Keough E, Roberts J, Koeplinger K, Lyman M, Fauty S, Carlini E, Stern M, Zhang R, Yeh S, Mahan E, Wang Y, Slaughter D, Gindy M, Raab C, Thompson C, Hochman J. Xu Y, et al. Among authors: koeplinger k. Mol Pharm. 2014 May 5;11(5):1424-34. doi: 10.1021/mp400584h. Epub 2014 Apr 1. Mol Pharm. 2014. PMID: 24588618

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