Fisher RP - Search Results

1

Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation.

Merrick KA, Wohlbold L, Zhang C, Allen JJ, Horiuchi D, Huskey NE, Goga A, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: fisher rp. Mol Cell. 2011 Jun 10;42(5):624-36. doi: 10.1016/j.molcel.2011.03.031. Mol Cell. 2011. PMID: 21658603 Free PMC article.

2

Directed evolution to bypass cyclin requirements for the Cdc28p cyclin-dependent kinase.

Levine K, Kiang L, Jacobson MD, Fisher RP, Cross FR. Levine K, et al. Among authors: fisher rp. Mol Cell. 1999 Sep;4(3):353-63. doi: 10.1016/s1097-2765(00)80337-8. Mol Cell. 1999. PMID: 10518216 Free article.

3

Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast.

Lee KM, Miklos I, Du H, Watt S, Szilagyi Z, Saiz JE, Madabhushi R, Penkett CJ, Sipiczki M, Bähler J, Fisher RP. Lee KM, et al. Among authors: fisher rp. Mol Biol Cell. 2005 Jun;16(6):2734-45. doi: 10.1091/mbc.e04-11-0982. Epub 2005 Apr 13. Mol Biol Cell. 2005. PMID: 15829570 Free PMC article.

4

Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.

Larochelle S, Batliner J, Gamble MJ, Barboza NM, Kraybill BC, Blethrow JD, Shokat KM, Fisher RP. Larochelle S, et al. Among authors: fisher rp. Nat Struct Mol Biol. 2006 Jan;13(1):55-62. doi: 10.1038/nsmb1028. Epub 2005 Dec 4. Nat Struct Mol Biol. 2006. PMID: 16327805

5

The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity.

Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP. Wohlbold L, et al. Among authors: fisher rp. Cell Cycle. 2006 Mar;5(5):546-54. doi: 10.4161/cc.5.5.2541. Epub 2006 Mar 1. Cell Cycle. 2006. PMID: 16552187

6

Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.

Burkard ME, Randall CL, Larochelle S, Zhang C, Shokat KM, Fisher RP, Jallepalli PV. Burkard ME, et al. Among authors: fisher rp. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4383-8. doi: 10.1073/pnas.0701140104. Epub 2007 Mar 6. Proc Natl Acad Sci U S A. 2007. PMID: 17360533 Free PMC article.

7

Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, Zhang C, Shokat KM, Jallepalli PV, Fisher RP. Larochelle S, et al. Among authors: fisher rp. Mol Cell. 2007 Mar 23;25(6):839-50. doi: 10.1016/j.molcel.2007.02.003. Mol Cell. 2007. PMID: 17386261 Free PMC article.

8

Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.

Sordet O, Larochelle S, Nicolas E, Stevens EV, Zhang C, Shokat KM, Fisher RP, Pommier Y. Sordet O, et al. Among authors: fisher rp. J Mol Biol. 2008 Sep 5;381(3):540-9. doi: 10.1016/j.jmb.2008.06.028. Epub 2008 Jun 17. J Mol Biol. 2008. PMID: 18588899 Free PMC article.

9

Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells.

Merrick KA, Larochelle S, Zhang C, Allen JJ, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: fisher rp. Mol Cell. 2008 Dec 5;32(5):662-72. doi: 10.1016/j.molcel.2008.10.022. Mol Cell. 2008. PMID: 19061641 Free PMC article.

10

TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast.

Viladevall L, St Amour CV, Rosebrock A, Schneider S, Zhang C, Allen JJ, Shokat KM, Schwer B, Leatherwood JK, Fisher RP. Viladevall L, et al. Among authors: fisher rp. Mol Cell. 2009 Mar 27;33(6):738-51. doi: 10.1016/j.molcel.2009.01.029. Mol Cell. 2009. PMID: 19328067 Free PMC article.

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