Wohlbold L - Search Results

1

Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation.

Merrick KA, Wohlbold L, Zhang C, Allen JJ, Horiuchi D, Huskey NE, Goga A, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: wohlbold l. Mol Cell. 2011 Jun 10;42(5):624-36. doi: 10.1016/j.molcel.2011.03.031. Mol Cell. 2011. PMID: 21658603 Free PMC article.

2

The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity.

Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP. Wohlbold L, et al. Cell Cycle. 2006 Mar;5(5):546-54. doi: 10.4161/cc.5.5.2541. Epub 2006 Mar 1. Cell Cycle. 2006. PMID: 16552187

3

Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, Zhang C, Shokat KM, Jallepalli PV, Fisher RP. Larochelle S, et al. Among authors: wohlbold l. Mol Cell. 2007 Mar 23;25(6):839-50. doi: 10.1016/j.molcel.2007.02.003. Mol Cell. 2007. PMID: 17386261 Free PMC article.

4

Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage.

Wohlbold L, Fisher RP. Wohlbold L, et al. DNA Repair (Amst). 2009 Sep 2;8(9):1018-24. doi: 10.1016/j.dnarep.2009.04.009. Epub 2009 May 22. DNA Repair (Amst). 2009. PMID: 19464967 Free PMC article. Review.

5

Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells.

Wohlbold L, Merrick KA, De S, Amat R, Kim JH, Larochelle S, Allen JJ, Zhang C, Shokat KM, Petrini JH, Fisher RP. Wohlbold L, et al. PLoS Genet. 2012 Aug;8(8):e1002935. doi: 10.1371/journal.pgen.1002935. Epub 2012 Aug 23. PLoS Genet. 2012. PMID: 22927831 Free PMC article.

6

Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways.

Horiuchi D, Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A. Horiuchi D, et al. Among authors: wohlbold l. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1019-27. doi: 10.1073/pnas.1111317109. Epub 2012 Apr 3. Proc Natl Acad Sci U S A. 2012. PMID: 22474407 Free PMC article.

7

The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.

Grüner S, Peter D, Weber R, Wohlbold L, Chung MY, Weichenrieder O, Valkov E, Igreja C, Izaurralde E. Grüner S, et al. Among authors: wohlbold l. Mol Cell. 2016 Nov 3;64(3):467-479. doi: 10.1016/j.molcel.2016.09.020. Epub 2016 Oct 20. Mol Cell. 2016. PMID: 27773676 Free article.

8

Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.

Teplova M, Wohlbold L, Khin NW, Izaurralde E, Patel DJ. Teplova M, et al. Among authors: wohlbold l. Nat Struct Mol Biol. 2011 Aug 7;18(9):990-8. doi: 10.1038/nsmb.2094. Nat Struct Mol Biol. 2011. PMID: 21822283 Free PMC article.

9

Molecular architecture of 4E-BP translational inhibitors bound to eIF4E.

Peter D, Igreja C, Weber R, Wohlbold L, Weiler C, Ebertsch L, Weichenrieder O, Izaurralde E. Peter D, et al. Among authors: wohlbold l. Mol Cell. 2015 Mar 19;57(6):1074-1087. doi: 10.1016/j.molcel.2015.01.017. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702871 Free article.

10

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.

Huntzinger E, Kuzuoglu-Öztürk D, Braun JE, Eulalio A, Wohlbold L, Izaurralde E. Huntzinger E, et al. Among authors: wohlbold l. Nucleic Acids Res. 2013 Jan;41(2):978-94. doi: 10.1093/nar/gks1078. Epub 2012 Nov 21. Nucleic Acids Res. 2013. PMID: 23172285 Free PMC article.

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