Eizirik DL - Search Results

1

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death.

Arif S, Moore F, Marks K, Bouckenooghe T, Dayan CM, Planas R, Vives-Pi M, Powrie J, Tree T, Marchetti P, Huang GC, Gurzov EN, Pujol-Borrell R, Eizirik DL, Peakman M. Arif S, et al. Among authors: eizirik dl. Diabetes. 2011 Aug;60(8):2112-9. doi: 10.2337/db10-1643. Epub 2011 Jun 9. Diabetes. 2011. PMID: 21659501 Free PMC article.

2

Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.

Ling Z, Van de Casteele M, Eizirik DL, Pipeleers DG. Ling Z, et al. Among authors: eizirik dl. Diabetes. 2000 Mar;49(3):340-5. doi: 10.2337/diabetes.49.3.340. Diabetes. 2000. PMID: 10868954

3

Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-kappaB and C/EBP.

Darville MI, Eizirik DL. Darville MI, et al. Among authors: eizirik dl. Diabetes. 2001 Aug;50(8):1741-8. doi: 10.2337/diabetes.50.8.1741. Diabetes. 2001. PMID: 11473033

4

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.

Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M, Eizirik DL. Heimberg H, et al. Among authors: eizirik dl. Diabetes. 2001 Oct;50(10):2219-24. doi: 10.2337/diabetes.50.10.2219. Diabetes. 2001. PMID: 11574401

5

Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.

Azevedo-Martins AK, Lortz S, Lenzen S, Curi R, Eizirik DL, Tiedge M. Azevedo-Martins AK, et al. Among authors: eizirik dl. Diabetes. 2003 Jan;52(1):93-101. doi: 10.2337/diabetes.52.1.93. Diabetes. 2003. PMID: 12502498

6

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.

Gysemans CA, Ladrière L, Callewaert H, Rasschaert J, Flamez D, Levy DE, Matthys P, Eizirik DL, Mathieu C. Gysemans CA, et al. Among authors: eizirik dl. Diabetes. 2005 Aug;54(8):2396-403. doi: 10.2337/diabetes.54.8.2396. Diabetes. 2005. PMID: 16046307

7

Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

Welsh N, Cnop M, Kharroubi I, Bugliani M, Lupi R, Marchetti P, Eizirik DL. Welsh N, et al. Among authors: eizirik dl. Diabetes. 2005 Nov;54(11):3238-44. doi: 10.2337/diabetes.54.11.3238. Diabetes. 2005. PMID: 16249450

8

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.

Cnop M, Welsh N, Jonas JC, Jörns A, Lenzen S, Eizirik DL. Cnop M, et al. Among authors: eizirik dl. Diabetes. 2005 Dec;54 Suppl 2:S97-107. doi: 10.2337/diabetes.54.suppl_2.s97. Diabetes. 2005. PMID: 16306347 Review.

9

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.

Dogusan Z, García M, Flamez D, Alexopoulou L, Goldman M, Gysemans C, Mathieu C, Libert C, Eizirik DL, Rasschaert J. Dogusan Z, et al. Among authors: eizirik dl. Diabetes. 2008 May;57(5):1236-45. doi: 10.2337/db07-0844. Epub 2008 Jan 25. Diabetes. 2008. PMID: 18223009

10

Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.

Ortis F, Pirot P, Naamane N, Kreins AY, Rasschaert J, Moore F, Théâtre E, Verhaeghe C, Magnusson NE, Chariot A, Orntoft TF, Eizirik DL. Ortis F, et al. Among authors: eizirik dl. Diabetologia. 2008 Jul;51(7):1213-25. doi: 10.1007/s00125-008-0999-7. Epub 2008 May 8. Diabetologia. 2008. PMID: 18463842 Free article.

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