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Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension.
Soon E, Crosby A, Southwood M, Yang P, Tajsic T, Toshner M, Appleby S, Shanahan CM, Bloch KD, Pepke-Zaba J, Upton P, Morrell NW. Soon E, et al. Among authors: crosby a. Am J Respir Crit Care Med. 2015 Oct 1;192(7):859-72. doi: 10.1164/rccm.201408-1509OC. Am J Respir Crit Care Med. 2015. PMID: 26073741 Free PMC article.
Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease.
Long L, Crosby A, Yang X, Southwood M, Upton PD, Kim DK, Morrell NW. Long L, et al. Among authors: crosby a. Circulation. 2009 Feb 3;119(4):566-76. doi: 10.1161/CIRCULATIONAHA.108.821504. Epub 2009 Jan 19. Circulation. 2009. PMID: 19153267
Pulmonary vascular disease associated with schistosomiasis.
Kolosionek E, Crosby A, Harhay MO, Morrell N, Butrous G. Kolosionek E, et al. Among authors: crosby a. Expert Rev Anti Infect Ther. 2010 Dec;8(12):1467-73. doi: 10.1586/eri.10.124. Expert Rev Anti Infect Ther. 2010. PMID: 21133670 Review.
HIF2α-arginase axis is essential for the development of pulmonary hypertension.
Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: crosby a. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8801-6. doi: 10.1073/pnas.1602978113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432976 Free PMC article.
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP. Yang P, et al. Among authors: crosby a. Circulation. 2017 Mar 21;135(12):1160-1173. doi: 10.1161/CIRCULATIONAHA.116.023218. Epub 2017 Jan 30. Circulation. 2017. PMID: 28137936 Free PMC article.
455 results