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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: bedoui s. Cell Rep. 2023 Aug 29;42(8):113014. doi: 10.1016/j.celrep.2023.113014. Epub 2023 Aug 21. Cell Rep. 2023. PMID: 37605534 Free article.
A multi-organ map of the human immune system across age, sex and ethnicity.
Mangiola S, Milton M, Ranathunga N, Li-Wai-Suen C, Odainic A, Yang E, Hutchison W, Garnham A, Iskander J, Pal B, Yadav V, Rossello J, Carey VJ, Morgan M, Bedoui S, Kallies A, Papenfuss AT. Mangiola S, et al. Among authors: bedoui s. bioRxiv [Preprint]. 2024 Apr 29:2023.06.08.542671. doi: 10.1101/2023.06.08.542671. bioRxiv. 2024. PMID: 38746418 Free PMC article. Preprint.
CD4+ T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses.
Bawden EG, Wagner T, Schröder J, Effern M, Hinze D, Newland L, Attrill GH, Lee AR, Engel S, Freestone D, de Lima Moreira M, Gressier E, McBain N, Bachem A, Haque A, Dong R, Ferguson AL, Edwards JJ, Ferguson PM, Scolyer RA, Wilmott JS, Jewell CM, Brooks AG, Gyorki DE, Palendira U, Bedoui S, Waithman J, Hochheiser K, Hölzel M, Gebhardt T. Bawden EG, et al. Among authors: bedoui s. Sci Immunol. 2024 Jan 19;9(91):eadi9517. doi: 10.1126/sciimmunol.adi9517. Epub 2024 Jan 19. Sci Immunol. 2024. PMID: 38241401
Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells.
Caminschi I, Ahmet F, Heger K, Brady J, Nutt SL, Vremec D, Pietersz S, Lahoud MH, Schofield L, Hansen DS, O'Keeffe M, Smyth MJ, Bedoui S, Davey GM, Villadangos JA, Heath WR, Shortman K. Caminschi I, et al. Among authors: bedoui s. J Exp Med. 2007 Oct 29;204(11):2579-90. doi: 10.1084/jem.20071351. Epub 2007 Oct 8. J Exp Med. 2007. PMID: 17923506 Free PMC article.
120 results