Scott CL - Search Results

1

Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.

Fuertes Marraco SA, Scott CL, Bouillet P, Ives A, Masina S, Vremec D, Jansen ES, O'Reilly LA, Schneider P, Fasel N, Shortman K, Strasser A, Acha-Orbea H. Fuertes Marraco SA, et al. Among authors: scott cl. PLoS One. 2011;6(6):e20189. doi: 10.1371/journal.pone.0020189. Epub 2011 Jun 2. PLoS One. 2011. PMID: 21674051 Free PMC article.

2

Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival.

Villunger A, Scott C, Bouillet P, Strasser A. Villunger A, et al. Blood. 2003 Mar 15;101(6):2393-400. doi: 10.1182/blood-2002-07-2132. Epub 2002 Nov 14. Blood. 2003. PMID: 12433687 Free article.

3

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis.

Coultas L, Terzano S, Thomas T, Voss A, Reid K, Stanley EG, Scott CL, Bouillet P, Bartlett P, Ham J, Adams JM, Strasser A. Coultas L, et al. Among authors: scott cl. J Cell Sci. 2007 Jun 15;120(Pt 12):2044-52. doi: 10.1242/jcs.002063. Epub 2007 May 29. J Cell Sci. 2007. PMID: 17535852 Free PMC article.

4

Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic.

Cragg MS, Jansen ES, Cook M, Harris C, Strasser A, Scott CL. Cragg MS, et al. Among authors: scott cl. J Clin Invest. 2008 Nov;118(11):3651-9. doi: 10.1172/JCI35437. Epub 2008 Oct 23. J Clin Invest. 2008. PMID: 18949058 Free PMC article.

5

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis.

Michalak EM, Jansen ES, Happo L, Cragg MS, Tai L, Smyth GK, Strasser A, Adams JM, Scott CL. Michalak EM, et al. Among authors: scott cl. Cell Death Differ. 2009 May;16(5):684-96. doi: 10.1038/cdd.2008.195. Epub 2009 Jan 16. Cell Death Differ. 2009. PMID: 19148184 Free PMC article.

6

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics.

Cragg MS, Harris C, Strasser A, Scott CL. Cragg MS, et al. Among authors: scott cl. Nat Rev Cancer. 2009 May;9(5):321-6. doi: 10.1038/nrc2615. Epub 2009 Apr 3. Nat Rev Cancer. 2009. PMID: 19343035 Review.

7

Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.

Carrington EM, McKenzie MD, Jansen E, Myers M, Fynch S, Kos C, Strasser A, Kay TW, Scott CL, Allison J. Carrington EM, et al. Among authors: scott cl. Diabetes. 2009 Oct;58(10):2316-23. doi: 10.2337/db08-1602. Epub 2009 Jul 6. Diabetes. 2009. PMID: 19581414 Free PMC article.

8

Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.

McKenzie MD, Jamieson E, Jansen ES, Scott CL, Huang DC, Bouillet P, Allison J, Kay TW, Strasser A, Thomas HE. McKenzie MD, et al. Among authors: scott cl. Diabetes. 2010 Mar;59(3):644-52. doi: 10.2337/db09-1151. Epub 2009 Dec 3. Diabetes. 2010. PMID: 19959756 Free PMC article.

9

c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.

Thien CB, Dagger SA, Steer JH, Koentgen F, Jansen ES, Scott CL, Langdon WY. Thien CB, et al. Among authors: scott cl. J Biol Chem. 2010 Apr 2;285(14):10969-81. doi: 10.1074/jbc.M109.094920. Epub 2010 Feb 4. J Biol Chem. 2010. PMID: 20133944 Free PMC article.

10

Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.

Michalak EM, Vandenberg CJ, Delbridge AR, Wu L, Scott CL, Adams JM, Strasser A. Michalak EM, et al. Among authors: scott cl. Genes Dev. 2010 Aug 1;24(15):1608-13. doi: 10.1101/gad.1940110. Genes Dev. 2010. PMID: 20679396 Free PMC article.

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