Hickey RD - Search Results

1

Efficient production of Fah-null heterozygote pigs by chimeric adeno-associated virus-mediated gene knockout and somatic cell nuclear transfer.

Hickey RD, Lillegard JB, Fisher JE, McKenzie TJ, Hofherr SE, Finegold MJ, Nyberg SL, Grompe M. Hickey RD, et al. Hepatology. 2011 Oct;54(4):1351-9. doi: 10.1002/hep.24490. Epub 2011 Aug 9. Hepatology. 2011. PMID: 21674562 Free PMC article.

2

Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease.

Hickey RD, Mao SA, Glorioso J, Lillegard JB, Fisher JE, Amiot B, Rinaldo P, Harding CO, Marler R, Finegold MJ, Grompe M, Nyberg SL. Hickey RD, et al. Stem Cell Res. 2014 Jul;13(1):144-53. doi: 10.1016/j.scr.2014.05.003. Epub 2014 May 14. Stem Cell Res. 2014. PMID: 24879068 Free PMC article.

3

Ploidy reductions in murine fusion-derived hepatocytes.

Duncan AW, Hickey RD, Paulk NK, Culberson AJ, Olson SB, Finegold MJ, Grompe M. Duncan AW, et al. Among authors: hickey rd. PLoS Genet. 2009 Feb;5(2):e1000385. doi: 10.1371/journal.pgen.1000385. Epub 2009 Feb 20. PLoS Genet. 2009. PMID: 19229314 Free PMC article.

4

Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1.

Hickey RD, Mao SA, Glorioso J, Elgilani F, Amiot B, Chen H, Rinaldo P, Marler R, Jiang H, DeGrado TR, Suksanpaisan L, O'Connor MK, Freeman BL, Ibrahim SH, Peng KW, Harding CO, Ho CS, Grompe M, Ikeda Y, Lillegard JB, Russell SJ, Nyberg SL. Hickey RD, et al. Sci Transl Med. 2016 Jul 27;8(349):349ra99. doi: 10.1126/scitranslmed.aaf3838. Sci Transl Med. 2016. PMID: 27464750 Free PMC article.

5

Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1.

Elgilani F, Mao SA, Glorioso JM, Yin M, Iankov ID, Singh A, Amiot B, Rinaldo P, Marler RJ, Ehman RL, Grompe M, Lillegard JB, Hickey RD, Nyberg SL. Elgilani F, et al. Among authors: hickey rd. Am J Pathol. 2017 Jan;187(1):33-41. doi: 10.1016/j.ajpath.2016.09.013. Epub 2016 Nov 14. Am J Pathol. 2017. PMID: 27855279 Free PMC article.

6

Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1.

Hickey RD, Nicolas CT, Allen K, Mao S, Elgilani F, Glorioso J, Amiot B, VanLith C, Guthman R, Du Z, Chen H, Harding CO, Kaiser RA, Nyberg SL, Lillegard JB. Hickey RD, et al. Cell Transplant. 2019 Jan;28(1):79-88. doi: 10.1177/0963689718814188. Epub 2018 Nov 26. Cell Transplant. 2019. PMID: 30477316 Free PMC article.

7

The ploidy conveyor of mature hepatocytes as a source of genetic variation.

Duncan AW, Taylor MH, Hickey RD, Hanlon Newell AE, Lenzi ML, Olson SB, Finegold MJ, Grompe M. Duncan AW, et al. Among authors: hickey rd. Nature. 2010 Oct 7;467(7316):707-10. doi: 10.1038/nature09414. Epub 2010 Sep 22. Nature. 2010. PMID: 20861837 Free PMC article.

8

Curative Ex Vivo Hepatocyte-Directed Gene Editing in a Mouse Model of Hereditary Tyrosinemia Type 1.

VanLith C, Guthman R, Nicolas CT, Allen K, Du Z, Joo DJ, Nyberg SL, Lillegard JB, Hickey RD. VanLith C, et al. Among authors: hickey rd. Hum Gene Ther. 2018 Nov;29(11):1315-1326. doi: 10.1089/hum.2017.252. Epub 2018 Jun 22. Hum Gene Ther. 2018. PMID: 29764210 Free PMC article.

9

Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models.

Nicolas CT, Hickey RD, Allen KL, Du Z, Guthman RM, Kaiser RA, Amiot B, Bansal A, Pandey MK, Suksanpaisan L, DeGrado TR, Nyberg SL, Lillegard JB. Nicolas CT, et al. Among authors: hickey rd. Surgery. 2018 Sep;164(3):473-481. doi: 10.1016/j.surg.2018.04.012. Epub 2018 Jun 6. Surgery. 2018. PMID: 29884476 Free PMC article.

10

Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine.

Kaiser RA, Mao SA, Glorioso J, Amiot B, Nicolas CT, Allen KL, Du Z, VanLith CJ, Hickey RD, Nyberg SL, Lillegard JB. Kaiser RA, et al. Among authors: hickey rd. J Vis Exp. 2018 Nov 4;(141):10.3791/58399. doi: 10.3791/58399. J Vis Exp. 2018. PMID: 30451238 Free PMC article.

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