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Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis.
Fukata M, Shang L, Santaolalla R, Sotolongo J, Pastorini C, España C, Ungaro R, Harpaz N, Cooper HS, Elson G, Kosco-Vilbois M, Zaias J, Perez MT, Mayer L, Vamadevan AS, Lira SA, Abreu MT. Fukata M, et al. Among authors: abreu mt. Inflamm Bowel Dis. 2011 Jul;17(7):1464-73. doi: 10.1002/ibd.21527. Epub 2010 Nov 15. Inflamm Bowel Dis. 2011. PMID: 21674704 Free PMC article.
TLR signaling in the gut in health and disease.
Abreu MT, Fukata M, Arditi M. Abreu MT, et al. J Immunol. 2005 Apr 15;174(8):4453-60. doi: 10.4049/jimmunol.174.8.4453. J Immunol. 2005. PMID: 15814663 Review.
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis.
Fukata M, Michelsen KS, Eri R, Thomas LS, Hu B, Lukasek K, Nast CC, Lechago J, Xu R, Naiki Y, Soliman A, Arditi M, Abreu MT. Fukata M, et al. Among authors: abreu mt. Am J Physiol Gastrointest Liver Physiol. 2005 May;288(5):G1055-65. doi: 10.1152/ajpgi.00328.2004. Am J Physiol Gastrointest Liver Physiol. 2005. PMID: 15826931 Free article.
Diagnosis of colitis: making the initial diagnosis.
Abreu MT, Harpaz N. Abreu MT, et al. Clin Gastroenterol Hepatol. 2007 Mar;5(3):295-301. doi: 10.1016/j.cgh.2006.12.032. Clin Gastroenterol Hepatol. 2007. PMID: 17368227 Review.
Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors.
Fukata M, Chen A, Vamadevan AS, Cohen J, Breglio K, Krishnareddy S, Hsu D, Xu R, Harpaz N, Dannenberg AJ, Subbaramaiah K, Cooper HS, Itzkowitz SH, Abreu MT. Fukata M, et al. Among authors: abreu mt. Gastroenterology. 2007 Dec;133(6):1869-81. doi: 10.1053/j.gastro.2007.09.008. Epub 2007 Sep 14. Gastroenterology. 2007. PMID: 18054559 Free PMC article.
294 results