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Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis.
Fukata M, Shang L, Santaolalla R, Sotolongo J, Pastorini C, España C, Ungaro R, Harpaz N, Cooper HS, Elson G, Kosco-Vilbois M, Zaias J, Perez MT, Mayer L, Vamadevan AS, Lira SA, Abreu MT. Fukata M, et al. Among authors: shang l. Inflamm Bowel Dis. 2011 Jul;17(7):1464-73. doi: 10.1002/ibd.21527. Epub 2010 Nov 15. Inflamm Bowel Dis. 2011. PMID: 21674704 Free PMC article.
TLR4 activates the β-catenin pathway to cause intestinal neoplasia.
Santaolalla R, Sussman DA, Ruiz JR, Davies JM, Pastorini C, España CL, Sotolongo J, Burlingame O, Bejarano PA, Philip S, Ahmed MM, Ko J, Dirisina R, Barrett TA, Shang L, Lira SA, Fukata M, Abreu MT. Santaolalla R, et al. Among authors: shang l. PLoS One. 2013 May 14;8(5):e63298. doi: 10.1371/journal.pone.0063298. Print 2013. PLoS One. 2013. PMID: 23691015 Free PMC article.
Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine.
Shang L, Thirunarayanan N, Viejo-Borbolla A, Martin AP, Bogunovic M, Marchesi F, Unkeless JC, Ho Y, Furtado GC, Alcami A, Merad M, Mayer L, Lira SA. Shang L, et al. Gastroenterology. 2009 Sep;137(3):1006-18, 1018.e1-3. doi: 10.1053/j.gastro.2009.05.055. Epub 2009 Jun 6. Gastroenterology. 2009. PMID: 19501588 Free PMC article.
A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease.
Hatterer E, Shang L, Simonet P, Herren S, Daubeuf B, Teixeira S, Reilly J, Elson G, Nelson R, Gabay C, Sokolove J, McInnes IB, Kosco-Vilbois M, Ferlin W, Monnet E, De Min C. Hatterer E, et al. Among authors: shang l. Arthritis Res Ther. 2016 Oct 6;18(1):224. doi: 10.1186/s13075-016-1128-5. Arthritis Res Ther. 2016. PMID: 27716430 Free PMC article.
2,225 results