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Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus.
Subramanian L, Sarkar A, Shetty AS, Muralidharan B, Padmanabhan H, Piper M, Monuki ES, Bach I, Gronostajski RM, Richards LJ, Tole S. Subramanian L, et al. Among authors: shetty as. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):E265-74. doi: 10.1073/pnas.1101109108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690374 Free PMC article.
Lhx2 regulates a cortex-specific mechanism for barrel formation.
Shetty AS, Godbole G, Maheshwari U, Padmanabhan H, Chaudhary R, Muralidharan B, Hou PS, Monuki ES, Kuo HC, Rema V, Tole S. Shetty AS, et al. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4913-21. doi: 10.1073/pnas.1311158110. Epub 2013 Nov 21. Proc Natl Acad Sci U S A. 2013. PMID: 24262147 Free PMC article.
Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus.
Muralidharan B, Keruzore M, Pradhan SJ, Roy B, Shetty AS, Kinare V, D'Souza L, Maheshwari U, Karmodiya K, Suresh A, Galande S, Bellefroid EJ, Tole S. Muralidharan B, et al. Among authors: shetty as. J Neurosci. 2017 Nov 15;37(46):11245-11254. doi: 10.1523/JNEUROSCI.1535-17.2017. Epub 2017 Oct 12. J Neurosci. 2017. PMID: 29025924 Free PMC article.
131 results