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Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.
Ramnauth J, Speed J, Maddaford SP, Dove P, Annedi SC, Renton P, Rakhit S, Andrews J, Silverman S, Mladenova G, Zinghini S, Nair S, Catalano C, Lee DK, De Felice M, Porreca F. Ramnauth J, et al. Among authors: speed j. J Med Chem. 2011 Aug 11;54(15):5562-75. doi: 10.1021/jm200648s. Epub 2011 Jul 8. J Med Chem. 2011. PMID: 21699209 Free PMC article.
1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors: lead optimization studies resulting in the identification of N-(1-(2-(methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a preclinical development candidate.
Ramnauth J, Renton P, Dove P, Annedi SC, Speed J, Silverman S, Mladenova G, Maddaford SP, Zinghini S, Rakhit S, Andrews J, Lee DK, Zhang D, Porreca F. Ramnauth J, et al. Among authors: speed j. J Med Chem. 2012 Mar 22;55(6):2882-93. doi: 10.1021/jm3000449. Epub 2012 Mar 1. J Med Chem. 2012. PMID: 22335555
Herbivore diversity effects on Arctic tundra ecosystems: a systematic review.
Barbero-Palacios L, Barrio IC, García Criado M, Kater I, Petit Bon M, Kolari THM, Bjørkås R, Trepel J, Lundgren E, Björnsdóttir K, Hwang BC, Bartra-Cabré L, Defourneaux M, Ramsay J, Lameris TK, Leffler AJ, Lock JG, Kuoppamaa MS, Kristensen JA, Bjorkman AD, Myers-Smith I, Lecomte N, Axmacher JC, Gilg O, Den Herder M, Pagneux EP, Skarin A, Sokolova N, Windirsch T, Wheeler HC, Serrano E, Virtanen T, Hik DS, Kaarlejärvi E, Speed JDM, Soininen EM. Barbero-Palacios L, et al. Among authors: speed jdm. Environ Evid. 2024 Mar 25;13(1):6. doi: 10.1186/s13750-024-00330-9. Environ Evid. 2024. PMID: 39294685 Free PMC article.
152 results