Walker LA - Search Results

1

DFT study on the radical anions formed by primaquine and its derivatives.

Liu H, Walker LA, Doerksen RJ. Liu H, et al. Among authors: walker la. Chem Res Toxicol. 2011 Sep 19;24(9):1476-85. doi: 10.1021/tx200094v. Epub 2011 Jul 7. Chem Res Toxicol. 2011. PMID: 21699254 Free PMC article.

2

Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.

Ganesan S, Tekwani BL, Sahu R, Tripathi LM, Walker LA. Ganesan S, et al. Among authors: walker la. Toxicol Appl Pharmacol. 2009 Nov 15;241(1):14-22. doi: 10.1016/j.taap.2009.07.012. Epub 2009 Jul 17. Toxicol Appl Pharmacol. 2009. PMID: 19616568

3

Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase.

Liu H, Walker LA, Nanayakkara NP, Doerksen RJ. Liu H, et al. Among authors: walker la. J Am Chem Soc. 2011 Feb 9;133(5):1172-5. doi: 10.1021/ja107472c. Epub 2011 Jan 18. J Am Chem Soc. 2011. PMID: 21244096 Free PMC article.

4

Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome.

Khan SI, Aumsuwan P, Khan IA, Walker LA, Dasmahapatra AK. Khan SI, et al. Among authors: walker la. Chem Res Toxicol. 2012 Jan 13;25(1):61-73. doi: 10.1021/tx200378c. Epub 2011 Oct 28. Chem Res Toxicol. 2012. PMID: 21992498 Review.

5

Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.

Ganesan S, Chaurasiya ND, Sahu R, Walker LA, Tekwani BL. Ganesan S, et al. Among authors: walker la. Toxicology. 2012 Mar 29;294(1):54-60. doi: 10.1016/j.tox.2012.01.015. Epub 2012 Feb 6. Toxicology. 2012. PMID: 22330256

6

Effect of antimalarial drug primaquine and its derivatives on the ionization potential of hemoglobin: A QM/MM study.

Liu H, Ding Y, Walker LA, Doerksen RJ. Liu H, et al. Among authors: walker la. Medchemcomm. 2013 Aug 1;4(8):1145-1147. doi: 10.1039/C3MD00045A. Medchemcomm. 2013. PMID: 23914290 Free PMC article.

7

Methemoglobin generation by 8-aminoquinolines: effect of substitution at 5-position of primaquine.

Liu H, Tekwani BL, Nanayakkara NP, Walker LA, Doerksen RJ. Liu H, et al. Among authors: walker la. Chem Res Toxicol. 2013 Dec 16;26(12):1801-9. doi: 10.1021/tx400067a. Epub 2013 Nov 13. Chem Res Toxicol. 2013. PMID: 24224488

8

Synthesis of [13C6]primaquine.

Herath HM, McChesney JD, Walker LA, Nanayakkara NP. Herath HM, et al. Among authors: walker la. J Labelled Comp Radiopharm. 2013 Jun 15;56(7):341-3. doi: 10.1002/jlcr.3039. Epub 2013 Mar 12. J Labelled Comp Radiopharm. 2013. PMID: 24285435

9

Hydroxylated derivatives of NPC1161: theoretical insights into their potential toxicity and the feasibility and regioselectivity of their formation.

Ding Y, Liu H, Nanayakkara NP, Khan IA, Tekwani BL, Walker LA, Doerksen RJ. Ding Y, et al. Among authors: walker la. J Phys Chem A. 2014 Jul 24;118(29):5501-7. doi: 10.1021/jp502612t. Epub 2014 Jul 11. J Phys Chem A. 2014. PMID: 24956138 Free PMC article.

10

Computational Study on the Effect of Exocyclic Substituents on the Ionization Potential of Primaquine: Insights into the Design of Primaquine-Based Antimalarial Drugs with Less Methemoglobin Generation.

Liu H, Ding Y, Walker LA, Doerksen RJ. Liu H, et al. Among authors: walker la. Chem Res Toxicol. 2015 Feb 16;28(2):169-74. doi: 10.1021/tx500230t. Epub 2015 Jan 27. Chem Res Toxicol. 2015. PMID: 25222923 Free PMC article.

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