van Aelst K - Search Results

1

Recombination hotspots and single-stranded DNA binding proteins couple DNA translocation to DNA unwinding by the AddAB helicase-nuclease.

Yeeles JT, van Aelst K, Dillingham MS, Moreno-Herrero F. Yeeles JT, et al. Among authors: van aelst k. Mol Cell. 2011 Jun 24;42(6):806-16. doi: 10.1016/j.molcel.2011.04.012. Mol Cell. 2011. PMID: 21700225 Free article.

2

Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes.

Chand MK, Nirwan N, Diffin FM, van Aelst K, Kulkarni M, Pernstich C, Szczelkun MD, Saikrishnan K. Chand MK, et al. Among authors: van aelst k. Nat Chem Biol. 2015 Nov;11(11):870-7. doi: 10.1038/nchembio.1926. Epub 2015 Sep 21. Nat Chem Biol. 2015. PMID: 26389736 Free PMC article.

3

Mapping DNA cleavage by the Type ISP restriction-modification enzymes following long-range communication between DNA sites in different orientations.

van Aelst K, Saikrishnan K, Szczelkun MD. van Aelst K, et al. Nucleic Acids Res. 2015 Dec 2;43(21):10430-43. doi: 10.1093/nar/gkv1129. Epub 2015 Oct 26. Nucleic Acids Res. 2015. PMID: 26507855 Free PMC article.

4

DNA cleavage by Type ISP Restriction-Modification enzymes is initially targeted to the 3'-5' strand.

van Aelst K, Šišáková E, Szczelkun MD. van Aelst K, et al. Nucleic Acids Res. 2013 Jan;41(2):1081-90. doi: 10.1093/nar/gks1210. Epub 2012 Dec 5. Nucleic Acids Res. 2013. PMID: 23221632 Free PMC article.

5

Dissociation from DNA of Type III Restriction-Modification enzymes during helicase-dependent motion and following endonuclease activity.

Tóth J, van Aelst K, Salmons H, Szczelkun MD. Tóth J, et al. Among authors: van aelst k. Nucleic Acids Res. 2012 Aug;40(14):6752-64. doi: 10.1093/nar/gks328. Epub 2012 Apr 20. Nucleic Acids Res. 2012. PMID: 22523084 Free PMC article.

6

The Type ISP Restriction-Modification enzymes LlaBIII and LlaGI use a translocation-collision mechanism to cleave non-specific DNA distant from their recognition sites.

Šišáková E, van Aelst K, Diffin FM, Szczelkun MD. Šišáková E, et al. Among authors: van aelst k. Nucleic Acids Res. 2013 Jan;41(2):1071-80. doi: 10.1093/nar/gks1209. Epub 2012 Dec 7. Nucleic Acids Res. 2013. PMID: 23222132 Free PMC article.

7

Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat.

van Aelst K, Tóth J, Ramanathan SP, Schwarz FW, Seidel R, Szczelkun MD. van Aelst K, et al. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9123-8. doi: 10.1073/pnas.1001637107. Epub 2010 Apr 30. Proc Natl Acad Sci U S A. 2010. PMID: 20435912 Free PMC article.

8

Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes.

Kulkarni M, Nirwan N, van Aelst K, Szczelkun MD, Saikrishnan K. Kulkarni M, et al. Among authors: van aelst k. Nucleic Acids Res. 2016 May 19;44(9):4396-408. doi: 10.1093/nar/gkw154. Epub 2016 Mar 14. Nucleic Acids Res. 2016. PMID: 26975655 Free PMC article.

9

The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a.

van Aelst K, Martínez-Santiago CJ, Cross SJ, Szczelkun MD. van Aelst K, et al. Genes (Basel). 2019 Feb 22;10(2):169. doi: 10.3390/genes10020169. Genes (Basel). 2019. PMID: 30813348 Free PMC article.

10

5' modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage.

Mullally G, van Aelst K, Naqvi MM, Diffin FM, Karvelis T, Gasiunas G, Siksnys V, Szczelkun MD. Mullally G, et al. Among authors: van aelst k. Nucleic Acids Res. 2020 Jul 9;48(12):6811-6823. doi: 10.1093/nar/gkaa477. Nucleic Acids Res. 2020. PMID: 32496535 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

19 results

Search Page

Filters