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Sex differences in H7N9 influenza A virus pathogenesis.
Hoffmann J, Otte A, Thiele S, Lotter H, Shu Y, Gabriel G. Hoffmann J, et al. Among authors: otte a. Vaccine. 2015 Dec 8;33(49):6949-54. doi: 10.1016/j.vaccine.2015.08.044. Epub 2015 Aug 25. Vaccine. 2015. PMID: 26319064
Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration.
Bedau T, Peters F, Prox J, Arnold P, Schmidt F, Finkernagel M, Köllmann S, Wichert R, Otte A, Ohler A, Stirnberg M, Lucius R, Koudelka T, Tholey A, Biasin V, Pietrzik CU, Kwapiszewska G, Becker-Pauly C. Bedau T, et al. Among authors: otte a. FASEB J. 2017 Mar;31(3):1226-1237. doi: 10.1096/fj.201601113R. Epub 2016 Dec 21. FASEB J. 2017. PMID: 28003343
Accordingly, deficiency of meprin beta in Mep1b(-/-) mice resulted in significantly increased CD99 protein levels in the lung. Therefore, meprin beta could serve as a therapeutic target, given that in a proof-of-concept approach we showed accumulation of CD99 protei …
Accordingly, deficiency of meprin beta in Mep1b(-/-) mice resulted in significantly increased CD99 protein levels in the lung. Therefore, me …
355 results