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A strategy for liquid chromatography/tandem mass spectrometry based quantitation of pegylated protein drugs in plasma using plasma protein precipitation with water-miscible organic solvents and subsequent trypsin digestion to generate surrogate peptides for detection.
Wu ST, Ouyang Z, Olah TV, Jemal M. Wu ST, et al. Among authors: jemal m. Rapid Commun Mass Spectrom. 2011 Jan 30;25(2):281-90. doi: 10.1002/rcm.4856. Rapid Commun Mass Spectrom. 2011. PMID: 21192023
A simplified and completely automated workflow for regulated LC-MS/MS bioanalysis using cap-piercing direct sampling and evaporation-free solid phase extraction.
Zheng N, Buzescu A, Pasas-Farmer S, Arnold ME, Ouyang Z, Jemal M, Peng Q, Van Vleet T, Zeng J. Zheng N, et al. Among authors: jemal m. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15;921-922:64-74. doi: 10.1016/j.jchromb.2013.01.028. Epub 2013 Feb 4. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23435343
Negative ion electrospray high-performance liquid chromatography-mass spectrometry method development for determination of a highly polar phosphonic acid/sulfonic acid compound in plasma. Optimization of ammonium acetate concentration and in-source collision-induced dissociation.
Jemal M, Almond R, Ouyang Z, Teitz D. Jemal M, et al. J Chromatogr B Biomed Sci Appl. 1997 Dec 5;703(1-2):167-75. doi: 10.1016/s0378-4347(97)00427-1. J Chromatogr B Biomed Sci Appl. 1997. PMID: 9448073
155 results