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Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor.
Hamberg P, Woo MM, Chen LC, Verweij J, Porro MG, Zhao L, Li W, van der Biessen D, Sharma S, Hengelage T, de Jonge M. Hamberg P, et al. Among authors: woo mm. Cancer Chemother Pharmacol. 2011 Sep;68(3):805-13. doi: 10.1007/s00280-011-1693-x. Epub 2011 Jun 26. Cancer Chemother Pharmacol. 2011. PMID: 21706316 Free PMC article. Clinical Trial.
The effect of food on the bioavailability of panobinostat, an orally active pan-histone deacetylase inhibitor, in patients with advanced cancer.
Shapiro GI, Frank R, Dandamudi UB, Hengelage T, Zhao L, Gazi L, Porro MG, Woo MM, Lewis LD. Shapiro GI, et al. Among authors: woo mm. Cancer Chemother Pharmacol. 2012 Feb;69(2):555-62. doi: 10.1007/s00280-011-1758-x. Epub 2011 Nov 6. Cancer Chemother Pharmacol. 2012. PMID: 22057852 Free PMC article. Clinical Trial.
27 results