Laurent G - Search Results

1

Peptides targeting estrogen receptor alpha-potential applications for breast cancer treatment.

Leclercq G, Gallo D, Cossy J, Laïos I, Larsimont D, Laurent G, Jacquot Y. Leclercq G, et al. Among authors: laurent g. Curr Pharm Des. 2011;17(25):2632-53. doi: 10.2174/138161211797416048. Curr Pharm Des. 2011. PMID: 21728983 Review.

2

Mechanisms governing the accumulation of estrogen receptor alpha in MCF-7 breast cancer cells treated with hydroxytamoxifen and related antiestrogens.

Laïos I, Journe F, Laurent G, Nonclercq D, Toillon RA, Seo HS, Leclercq G. Laïos I, et al. Among authors: laurent g. J Steroid Biochem Mol Biol. 2003 Nov;87(2-3):207-21. doi: 10.1016/j.jsbmb.2003.09.011. J Steroid Biochem Mol Biol. 2003. PMID: 14672741

3

Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells.

Laïos I, Journé F, Nonclercq D, Vidal DS, Toillon RA, Laurent G, Leclercq G. Laïos I, et al. Among authors: laurent g. J Steroid Biochem Mol Biol. 2005 Mar;94(4):347-59. doi: 10.1016/j.jsbmb.2005.02.005. J Steroid Biochem Mol Biol. 2005. PMID: 15857754

4

Estrogen receptor alpha: impact of ligands on intracellular shuttling and turnover rate in breast cancer cells.

Leclercq G, Lacroix M, Laïos I, Laurent G. Leclercq G, et al. Among authors: laurent g. Curr Cancer Drug Targets. 2006 Feb;6(1):39-64. doi: 10.2174/156800906775471716. Curr Cancer Drug Targets. 2006. PMID: 16475975 Review.

5

Calmodulin-independent, agonistic properties of a peptide containing the calmodulin binding site of estrogen receptor alpha.

Gallo D, Jacquemotte F, Cleeren A, Laïos I, Hadiy S, Rowlands MG, Caille O, Nonclercq D, Laurent G, Jacquot Y, Leclercq G. Gallo D, et al. Among authors: laurent g. Mol Cell Endocrinol. 2007 Mar 30;268(1-2):37-49. doi: 10.1016/j.mce.2007.01.012. Epub 2007 Jan 25. Mol Cell Endocrinol. 2007. PMID: 17316976

6

Effects of (R,S)/(S,R)-4,5-bis(2-chloro-4-hydroxyphenyl)-2-imidazolines and (R,S)/(S,R)-2,3-bis(2-chloro-4-hydroxyphenyl)piperazines on estrogen receptor alpha level and transcriptional activity in MCF-7 cells.

Laïos I, Cleeren A, Leclercq G, Nonclercq D, Laurent G, Schlenk M, Wellner A, Gust R. Laïos I, et al. Among authors: laurent g. Biochem Pharmacol. 2007 Oct 1;74(7):1029-38. doi: 10.1016/j.bcp.2007.06.045. Epub 2007 Jul 7. Biochem Pharmacol. 2007. PMID: 17706611

7

Trophic effect in MCF-7 cells of ERalpha17p, a peptide corresponding to a platform regulatory motif of the estrogen receptor alpha--underlying mechanisms.

Gallo D, Haddad I, Duvillier H, Jacquemotte F, Laïos I, Laurent G, Jacquot Y, Vinh J, Leclercq G. Gallo D, et al. Among authors: laurent g. J Steroid Biochem Mol Biol. 2008 Mar;109(1-2):138-49. doi: 10.1016/j.jsbmb.2007.12.012. Epub 2007 Dec 28. J Steroid Biochem Mol Biol. 2008. PMID: 18262408

8

Regulatory function of the P295-T311 motif of the estrogen receptor alpha - does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses?

Gallo D, Haddad I, Laurent G, Vinh J, Jacquemotte F, Jacquot Y, Leclercq G. Gallo D, et al. Among authors: laurent g. Nucl Recept Signal. 2008 Apr 18;6:e007. doi: 10.1621/nrs.06007. Nucl Recept Signal. 2008. PMID: 18432312 Free PMC article.

9

Calmodulin, a regulatory partner of the estrogen receptor alpha in breast cancer cells.

Gallo D, Jacquot Y, Laurent G, Leclercq G. Gallo D, et al. Among authors: laurent g. Mol Cell Endocrinol. 2008 Sep 10;291(1-2):20-6. doi: 10.1016/j.mce.2008.04.011. Epub 2008 Apr 26. Mol Cell Endocrinol. 2008. PMID: 18524472 Free article. Review.

10

Capacity of type I and II ligands to confer to estrogen receptor alpha an appropriate conformation for the recruitment of coactivators containing a LxxLL motif-Relationship with the regulation of receptor level and ERE-dependent transcription in MCF-7 cells.

Bourgoin-Voillard S, Gallo D, Laïos I, Cleeren A, Bali LE, Jacquot Y, Nonclercq D, Laurent G, Tabet JC, Leclercq G. Bourgoin-Voillard S, et al. Among authors: laurent g. Biochem Pharmacol. 2010 Mar 1;79(5):746-57. doi: 10.1016/j.bcp.2009.10.015. Epub 2009 Oct 29. Biochem Pharmacol. 2010. PMID: 19879249

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