Iwakuma T - Search Results

1

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.

Pant V, Xiong S, Iwakuma T, Quintás-Cardama A, Lozano G. Pant V, et al. Among authors: iwakuma t. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11995-2000. doi: 10.1073/pnas.1102241108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730132 Free PMC article.

2

Characterization of an Mtbp Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model.

Ranjan A, Thoenen EA, Kaida A, Wood S, Van Dyke T, Iwakuma T. Ranjan A, et al. Among authors: iwakuma t. Cancers (Basel). 2023 Sep 16;15(18):4596. doi: 10.3390/cancers15184596. Cancers (Basel). 2023. PMID: 37760565 Free PMC article.

3

MDM2, an introduction.

Iwakuma T, Lozano G. Iwakuma T, et al. Mol Cancer Res. 2003 Dec;1(14):993-1000. Mol Cancer Res. 2003. PMID: 14707282 Review.

4

Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.

Iwakuma T, Parant JM, Fasulo M, Zwart E, Jacks T, de Vries A, Lozano G. Iwakuma T, et al. Oncogene. 2004 Oct 7;23(46):7644-50. doi: 10.1038/sj.onc.1207793. Oncogene. 2004. PMID: 15361844

5

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

Bruins W, Zwart E, Attardi LD, Iwakuma T, Hoogervorst EM, Beems RB, Miranda B, van Oostrom CT, van den Berg J, van den Aardweg GJ, Lozano G, van Steeg H, Jacks T, de Vries A. Bruins W, et al. Among authors: iwakuma t. Mol Cell Biol. 2004 Oct;24(20):8884-94. doi: 10.1128/MCB.24.20.8884-8894.2004. Mol Cell Biol. 2004. PMID: 15456863 Free PMC article.

6

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM, Valentin-Vega YA, Terzian T, Caldwell LC, Strong LC, El-Naggar AK, Lozano G. Lang GA, et al. Among authors: iwakuma t. Cell. 2004 Dec 17;119(6):861-72. doi: 10.1016/j.cell.2004.11.006. Cell. 2004. PMID: 15607981 Free article.

7

Li-Fraumeni syndrome: a p53 family affair.

Iwakuma T, Lozano G, Flores ER. Iwakuma T, et al. Cell Cycle. 2005 Jul;4(7):865-7. doi: 10.4161/cc.4.7.1800. Epub 2005 Jul 4. Cell Cycle. 2005. PMID: 15917654 Review.

8

Crippling p53 activities via knock-in mutations in mouse models.

Iwakuma T, Lozano G. Iwakuma T, et al. Oncogene. 2007 Apr 2;26(15):2177-84. doi: 10.1038/sj.onc.1210278. Oncogene. 2007. PMID: 17401426 Review.

9

Mtbp haploinsufficiency in mice increases tumor metastasis.

Iwakuma T, Tochigi Y, Van Pelt CS, Caldwell LC, Terzian T, Parant JM, Chau GP, Koch JG, Eischen CM, Lozano G. Iwakuma T, et al. Oncogene. 2008 Mar 20;27(13):1813-20. doi: 10.1038/sj.onc.1210827. Epub 2007 Oct 1. Oncogene. 2008. PMID: 17906694

10

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss.

Terzian T, Suh YA, Iwakuma T, Post SM, Neumann M, Lang GA, Van Pelt CS, Lozano G. Terzian T, et al. Among authors: iwakuma t. Genes Dev. 2008 May 15;22(10):1337-44. doi: 10.1101/gad.1662908. Genes Dev. 2008. PMID: 18483220 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

105 results

Search Page

Filters