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Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data.
Tao Y, Ruan J, Yeh SH, Lu X, Wang Y, Zhai W, Cai J, Ling S, Gong Q, Chong Z, Qu Z, Li Q, Liu J, Yang J, Zheng C, Zeng C, Wang HY, Zhang J, Wang SH, Hao L, Dong L, Li W, Sun M, Zou W, Yu C, Li C, Liu G, Jiang L, Xu J, Huang H, Li C, Mi S, Zhang B, Chen B, Zhao W, Hu S, Zhuang SM, Shen Y, Shi S, Brown C, White KP, Chen DS, Chen PJ, Wu CI. Tao Y, et al. Among authors: hao l. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12042-7. doi: 10.1073/pnas.1108715108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730188 Free PMC article.
Identification of functional cooperative mutations of SETD2 in human acute leukemia.
Zhu X, He F, Zeng H, Ling S, Chen A, Wang Y, Yan X, Wei W, Pang Y, Cheng H, Hua C, Zhang Y, Yang X, Lu X, Cao L, Hao L, Dong L, Zou W, Wu J, Li X, Zheng S, Yan J, Zhou J, Zhang L, Mi S, Wang X, Zhang L, Zou Y, Chen Y, Geng Z, Wang J, Zhou J, Liu X, Wang J, Yuan W, Huang G, Cheng T, Wang QF. Zhu X, et al. Among authors: hao l. Nat Genet. 2014 Mar;46(3):287-93. doi: 10.1038/ng.2894. Epub 2014 Feb 9. Nat Genet. 2014. PMID: 24509477 Free PMC article.
Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution.
Ling S, Hu Z, Yang Z, Yang F, Li Y, Lin P, Chen K, Dong L, Cao L, Tao Y, Hao L, Chen Q, Gong Q, Wu D, Li W, Zhao W, Tian X, Hao C, Hungate EA, Catenacci DV, Hudson RR, Li WH, Lu X, Wu CI. Ling S, et al. Among authors: hao l, hao c. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6496-505. doi: 10.1073/pnas.1519556112. Epub 2015 Nov 11. Proc Natl Acad Sci U S A. 2015. PMID: 26561581 Free PMC article.
Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia.
Huang L, Liu D, Wang N, Ling S, Tang Y, Wu J, Hao L, Luo H, Hu X, Sheng L, Zhu L, Wang D, Luo Y, Shang Z, Xiao M, Mao X, Zhou K, Cao L, Dong L, Zheng X, Sui P, He J, Mo S, Yan J, Ao Q, Qiu L, Zhou H, Liu Q, Zhang H, Li J, Jin J, Fu L, Zhao W, Chen J, Du X, Qing G, Liu H, Liu X, Huang G, Ma D, Zhou J, Wang QF. Huang L, et al. Among authors: hao l. Cell Res. 2018 Feb;28(2):172-186. doi: 10.1038/cr.2017.146. Epub 2017 Nov 17. Cell Res. 2018. PMID: 29148541 Free PMC article.
Quartet DNA reference materials and datasets for comprehensively evaluating germline variant calling performance.
Ren L, Duan X, Dong L, Zhang R, Yang J, Gao Y, Peng R, Hou W, Liu Y, Li J, Yu Y, Zhang N, Shang J, Liang F, Wang D, Chen H, Sun L, Hao L; Quartet Project Team; Scherer A, Nordlund J, Xiao W, Xu J, Tong W, Hu X, Jia P, Ye K, Li J, Jin L, Hong H, Wang J, Fan S, Fang X, Zheng Y, Shi L. Ren L, et al. Among authors: hao l. Genome Biol. 2023 Nov 27;24(1):270. doi: 10.1186/s13059-023-03109-2. Genome Biol. 2023. PMID: 38012772 Free PMC article.
4,281 results