Blomme EA - Search Results

1

Global transcriptomic profiling using small volumes of whole blood: a cost-effective method for translational genomic biomarker identification in small animals.

Fricano MM, Ditewig AC, Jung PM, Liguori MJ, Blomme EA, Yang Y. Fricano MM, et al. Among authors: blomme ea. Int J Mol Sci. 2011;12(4):2502-17. doi: 10.3390/ijms12042502. Epub 2011 Apr 13. Int J Mol Sci. 2011. PMID: 21731455 Free PMC article.

2

Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.

Liguori MJ, Ditewig AC, Maddox JF, Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Waring JF, Ganey PE, Roth RA, Blomme EA. Liguori MJ, et al. Among authors: blomme ea. Int J Mol Sci. 2010 Nov 18;11(11):4697-714. doi: 10.3390/ijms11114697. Int J Mol Sci. 2010. PMID: 21151465 Free PMC article.

3

Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells.

Liguori MJ, Blomme EA, Waring JF. Liguori MJ, et al. Among authors: blomme ea. Drug Metab Dispos. 2008 Feb;36(2):223-33. doi: 10.1124/dmd.107.017608. Epub 2007 Oct 29. Drug Metab Dispos. 2008. PMID: 17967932

4

Role of cytochrome P450c17α in dibromoacetic acid-induced testicular toxicity in rats.

Carr TL, Ciurlionis R, Milicic I, Whitney K, Liguori MJ, Warder SE, Strakhova MI, Blomme EA. Carr TL, et al. Among authors: blomme ea. Arch Toxicol. 2011 May;85(5):513-23. doi: 10.1007/s00204-010-0600-2. Epub 2010 Nov 3. Arch Toxicol. 2011. PMID: 21046364

5

Transcriptomic evaluation of canine suspension-shipped and pre-plated hepatocytes: comparison to liver.

Ditewig AC, Cugier DJ, Liguori MJ, Yang Y, Blomme EA. Ditewig AC, et al. Among authors: blomme ea. Toxicol Mech Methods. 2013 Sep;23(7):479-90. doi: 10.3109/15376516.2013.796031. Epub 2013 Jun 14. Toxicol Mech Methods. 2013. PMID: 23581556

6

Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils.

Waring JF, Liguori MJ, Luyendyk JP, Maddox JF, Ganey PE, Stachlewitz RF, North C, Blomme EA, Roth RA. Waring JF, et al. Among authors: blomme ea. J Pharmacol Exp Ther. 2006 Mar;316(3):1080-7. doi: 10.1124/jpet.105.096347. Epub 2005 Nov 18. J Pharmacol Exp Ther. 2006. PMID: 16299187

7

Evaluation of the effects of serial phlebotomy on the transcriptome of major tissues and on the response to toxicants in rats.

Blomme EA, Ciurlionis R, Marsh KC, Waring JF, Yang Y. Blomme EA, et al. Toxicol Lett. 2008 Jan 30;176(2):138-48. doi: 10.1016/j.toxlet.2007.09.014. Epub 2007 Oct 9. Toxicol Lett. 2008. PMID: 18164877

8

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.

Blomme EA, Yang Y, Waring JF. Blomme EA, et al. Toxicol Lett. 2009 Apr 10;186(1):22-31. doi: 10.1016/j.toxlet.2008.09.017. Epub 2008 Oct 17. Toxicol Lett. 2009. PMID: 18996174 Review.

9

N-vinylpyrrolidone dimer, a novel formulation excipient, causes hepatic and thyroid hypertrophy through the induction of hepatic microsomal enzymes in rats.

Yang Y, Ciurlionis R, Kowalkowski K, Marsh KC, Bracken WM, Blomme EA. Yang Y, et al. Among authors: blomme ea. Toxicol Lett. 2012 Jan 5;208(1):82-91. doi: 10.1016/j.toxlet.2011.10.012. Epub 2011 Oct 20. Toxicol Lett. 2012. PMID: 22037397

10

AhR activation underlies the CYP1A autoinduction by A-998679 in rats.

Liguori MJ, Lee CH, Liu H, Ciurlionis R, Ditewig AC, Doktor S, Andracki ME, Gagne GD, Waring JF, Marsh KC, Gopalakrishnan M, Blomme EA, Yang Y. Liguori MJ, et al. Among authors: blomme ea. Front Genet. 2012 Oct 26;3:213. doi: 10.3389/fgene.2012.00213. eCollection 2012. Front Genet. 2012. PMID: 23112805 Free PMC article.

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