Bi C - Search Results

1

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.

Zhou J, Bi C, Cheong LL, Mahara S, Liu SC, Tay KG, Koh TL, Yu Q, Chng WJ. Zhou J, et al. Among authors: bi c. Blood. 2011 Sep 8;118(10):2830-9. doi: 10.1182/blood-2010-07-294827. Epub 2011 Jul 6. Blood. 2011. PMID: 21734239 Free article.

2

Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.

Zhou J, Bi C, Janakakumara JV, Liu SC, Chng WJ, Tay KG, Poon LF, Xie Z, Palaniyandi S, Yu H, Glaser KB, Albert DH, Davidsen SK, Chen CS. Zhou J, et al. Among authors: bi c. Blood. 2009 Apr 23;113(17):4052-62. doi: 10.1182/blood-2008-05-156422. Epub 2009 Jan 14. Blood. 2009. PMID: 19144991 Free article.

3

PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapy.

Zhou J, Bi C, Chng WJ, Cheong LL, Liu SC, Mahara S, Tay KG, Zeng Q, Li J, Guo K, Tan CP, Yu H, Albert DH, Chen CS. Zhou J, et al. Among authors: bi c. PLoS One. 2011 May 12;6(5):e19798. doi: 10.1371/journal.pone.0019798. PLoS One. 2011. PMID: 21589872 Free PMC article.

4

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.

Xie Z, Bi C, Cheong LL, Liu SC, Huang G, Zhou J, Yu Q, Chen CS, Chng WJ. Xie Z, et al. Among authors: bi c. PLoS One. 2011;6(6):e21583. doi: 10.1371/journal.pone.0021583. Epub 2011 Jun 24. PLoS One. 2011. PMID: 21720561 Free PMC article.

5

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma.

Ng SB, Yan J, Huang G, Selvarajan V, Tay JL, Lin B, Bi C, Tan J, Kwong YL, Shimizu N, Aozasa K, Chng WJ. Ng SB, et al. Among authors: bi c. Blood. 2011 Nov 3;118(18):4919-29. doi: 10.1182/blood-2011-07-364224. Epub 2011 Sep 14. Blood. 2011. PMID: 21921041 Free article.

6

EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity.

Yan J, Ng SB, Tay JL, Lin B, Koh TL, Tan J, Selvarajan V, Liu SC, Bi C, Wang S, Choo SN, Shimizu N, Huang G, Yu Q, Chng WJ. Yan J, et al. Among authors: bi c. Blood. 2013 May 30;121(22):4512-20. doi: 10.1182/blood-2012-08-450494. Epub 2013 Mar 25. Blood. 2013. PMID: 23529930 Free article.

7

EZH2 phosphorylation by JAK3 mediates a switch to noncanonical function in natural killer/T-cell lymphoma.

Yan J, Li B, Lin B, Lee PT, Chung TH, Tan J, Bi C, Lee XT, Selvarajan V, Ng SB, Yang H, Yu Q, Chng WJ. Yan J, et al. Among authors: bi c. Blood. 2016 Aug 18;128(7):948-58. doi: 10.1182/blood-2016-01-690701. Epub 2016 Jun 13. Blood. 2016. PMID: 27297789 Free article.

8

The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia.

Zhou J, Cheong LL, Liu SC, Chong PS, Mahara S, Bi C, Ong KO, Zeng Q, Chng WJ. Zhou J, et al. Among authors: bi c. Mol Cancer. 2012 Sep 21;11:72. doi: 10.1186/1476-4598-11-72. Mol Cancer. 2012. PMID: 22995644 Free PMC article.

9

Phosphatase of regenerating liver-3 is regulated by signal transducer and activator of transcription 3 in acute myeloid leukemia.

Zhou J, Chong PS, Lu X, Cheong LL, Bi C, Liu SC, Zhou Y, Tan TZ, Yang H, Chung TH, Zeng Q, Chng WJ. Zhou J, et al. Among authors: bi c. Exp Hematol. 2014 Dec;42(12):1041-52.e1-2. doi: 10.1016/j.exphem.2014.08.001. Epub 2014 Aug 17. Exp Hematol. 2014. PMID: 25139404 Free article.

10

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML.

Zhou J, Chan ZL, Bi C, Lu X, Chong PS, Chooi JY, Cheong LL, Liu SC, Ching YQ, Zhou Y, Osato M, Tan TZ, Ng CH, Ng SB, Wang S, Zeng Q, Chng WJ. Zhou J, et al. Among authors: bi c. Mol Cancer Res. 2017 Mar;15(3):294-303. doi: 10.1158/1541-7786.MCR-16-0275-T. Epub 2016 Dec 23. Mol Cancer Res. 2017. PMID: 28011885

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