Chng WJ - Search Results

1

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.

Zhou J, Bi C, Cheong LL, Mahara S, Liu SC, Tay KG, Koh TL, Yu Q, Chng WJ. Zhou J, et al. Among authors: chng wj. Blood. 2011 Sep 8;118(10):2830-9. doi: 10.1182/blood-2010-07-294827. Epub 2011 Jul 6. Blood. 2011. PMID: 21734239 Free article.

2

Gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma identifies new biologic insights with potential diagnostic and therapeutic applications.

Chng WJ, Remstein ED, Fonseca R, Bergsagel PL, Vrana JA, Kurtin PJ, Dogan A. Chng WJ, et al. Blood. 2009 Jan 15;113(3):635-45. doi: 10.1182/blood-2008-02-140996. Epub 2008 Oct 30. Blood. 2009. PMID: 18974375 Free PMC article.

3

Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.

Zhou J, Bi C, Janakakumara JV, Liu SC, Chng WJ, Tay KG, Poon LF, Xie Z, Palaniyandi S, Yu H, Glaser KB, Albert DH, Davidsen SK, Chen CS. Zhou J, et al. Among authors: chng wj. Blood. 2009 Apr 23;113(17):4052-62. doi: 10.1182/blood-2008-05-156422. Epub 2009 Jan 14. Blood. 2009. PMID: 19144991 Free article.

4

PCBP1 suppresses the translation of metastasis-associated PRL-3 phosphatase.

Wang H, Vardy LA, Tan CP, Loo JM, Guo K, Li J, Lim SG, Zhou J, Chng WJ, Ng SB, Li HX, Zeng Q. Wang H, et al. Among authors: chng wj. Cancer Cell. 2010 Jul 13;18(1):52-62. doi: 10.1016/j.ccr.2010.04.028. Cancer Cell. 2010. PMID: 20609352 Free article.

5

"Micro"-managing the MiRNome in SzS.

Chng WJ. Chng WJ. Blood. 2010 Aug 19;116(7):1021-2. doi: 10.1182/blood-2010-05-285189. Blood. 2010. PMID: 20724547 Free article. No abstract available.

6

Therapeutic potential of antisense oligodeoxynucleotides in downregulating p53 oncogenic mutations in cancers.

Xie Z, Chng WJ, Tay KG, Liu SC, Zhou J, Chen CS. Xie Z, et al. Among authors: chng wj. Biotechnol Lett. 2011 Feb;33(2):221-8. doi: 10.1007/s10529-010-0423-5. Epub 2010 Sep 30. Biotechnol Lett. 2011. PMID: 20882314

7

Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling.

Ng SB, Selvarajan V, Huang G, Zhou J, Feldman AL, Law M, Kwong YL, Shimizu N, Kagami Y, Aozasa K, Salto-Tellez M, Chng WJ. Ng SB, et al. Among authors: chng wj. J Pathol. 2011 Mar;223(4):496-510. doi: 10.1002/path.2823. Epub 2011 Jan 5. J Pathol. 2011. PMID: 21294123

8

PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapy.

Zhou J, Bi C, Chng WJ, Cheong LL, Liu SC, Mahara S, Tay KG, Zeng Q, Li J, Guo K, Tan CP, Yu H, Albert DH, Chen CS. Zhou J, et al. Among authors: chng wj. PLoS One. 2011 May 12;6(5):e19798. doi: 10.1371/journal.pone.0019798. PLoS One. 2011. PMID: 21589872 Free PMC article.

9

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.

Xie Z, Bi C, Cheong LL, Liu SC, Huang G, Zhou J, Yu Q, Chen CS, Chng WJ. Xie Z, et al. Among authors: chng wj. PLoS One. 2011;6(6):e21583. doi: 10.1371/journal.pone.0021583. Epub 2011 Jun 24. PLoS One. 2011. PMID: 21720561 Free PMC article.

10

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma.

Ng SB, Yan J, Huang G, Selvarajan V, Tay JL, Lin B, Bi C, Tan J, Kwong YL, Shimizu N, Aozasa K, Chng WJ. Ng SB, et al. Among authors: chng wj. Blood. 2011 Nov 3;118(18):4919-29. doi: 10.1182/blood-2011-07-364224. Epub 2011 Sep 14. Blood. 2011. PMID: 21921041 Free article.

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