Yu Q - Search Results

1

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.

Zhou J, Bi C, Cheong LL, Mahara S, Liu SC, Tay KG, Koh TL, Yu Q, Chng WJ. Zhou J, et al. Among authors: yu q. Blood. 2011 Sep 8;118(10):2830-9. doi: 10.1182/blood-2010-07-294827. Epub 2011 Jul 6. Blood. 2011. PMID: 21734239 Free article.

2

Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity.

Tan J, Zhuang L, Jiang X, Yang KK, Karuturi KM, Yu Q. Tan J, et al. Among authors: yu q. J Biol Chem. 2006 Apr 14;281(15):10508-15. doi: 10.1074/jbc.M512719200. Epub 2006 Feb 13. J Biol Chem. 2006. PMID: 16476732 Free article.

3

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q. Tan J, et al. Among authors: yu q. Genes Dev. 2007 May 1;21(9):1050-63. doi: 10.1101/gad.1524107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437993 Free PMC article.

4

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q. Jiang X, et al. Among authors: yu q. Cancer Cell. 2008 Jun;13(6):529-41. doi: 10.1016/j.ccr.2008.04.019. Cancer Cell. 2008. PMID: 18538736 Free PMC article.

5

Cancer gene silencing without DNA hypermethylation.

Yu Q. Yu Q. Epigenetics. 2008 Nov;3(6):315-7. doi: 10.4161/epi.3.6.7202. Epub 2008 Nov 14. Epigenetics. 2008. PMID: 19098450 Free article.

6

CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells.

Yang X, Karuturi RK, Sun F, Aau M, Yu K, Shao R, Miller LD, Tan PB, Yu Q. Yang X, et al. Among authors: yu q, yu k. PLoS One. 2009;4(4):e5011. doi: 10.1371/journal.pone.0005011. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340297 Free PMC article.

7

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.

Sun F, Chan E, Wu Z, Yang X, Marquez VE, Yu Q. Sun F, et al. Among authors: yu q. Mol Cancer Ther. 2009 Dec;8(12):3191-202. doi: 10.1158/1535-7163.MCT-09-0479. Mol Cancer Ther. 2009. PMID: 19934278 Free PMC article.

8

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.

Xie Z, Bi C, Cheong LL, Liu SC, Huang G, Zhou J, Yu Q, Chen CS, Chng WJ. Xie Z, et al. Among authors: yu q. PLoS One. 2011;6(6):e21583. doi: 10.1371/journal.pone.0021583. Epub 2011 Jun 24. PLoS One. 2011. PMID: 21720561 Free PMC article.

9

Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers.

Lee ST, Li Z, Wu Z, Aau M, Guan P, Karuturi RK, Liou YC, Yu Q. Lee ST, et al. Among authors: yu q. Mol Cell. 2011 Sep 2;43(5):798-810. doi: 10.1016/j.molcel.2011.08.011. Mol Cell. 2011. PMID: 21884980 Free article.

10

TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms.

Zhou J, Yu Q, Chng WJ. Zhou J, et al. Among authors: yu q. Int J Biochem Cell Biol. 2011 Dec;43(12):1668-73. doi: 10.1016/j.biocel.2011.09.005. Epub 2011 Sep 24. Int J Biochem Cell Biol. 2011. PMID: 21964212 Review.

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