Lin D - Search Results

1

Preparation of α-alkyl-β-amino acids via β-alanine Ni(II) complex.

Lin D, Lv L, Wang J, Ding X, Jiang H, Liu H. Lin D, et al. J Org Chem. 2011 Aug 19;76(16):6649-56. doi: 10.1021/jo200971k. Epub 2011 Jul 19. J Org Chem. 2011. PMID: 21736303

2

Efficient synthesis of symmetrical alpha,alpha-disubstituted beta-amino acids and alpha,alpha-disubstituted aldehydes via dialkylation of nucleophilic beta-alanine equivalent.

Lin D, Deng G, Wang J, Ding X, Jiang H, Liu H. Lin D, et al. J Org Chem. 2010 Mar 5;75(5):1717-22. doi: 10.1021/jo902699t. J Org Chem. 2010. PMID: 20141112

3

Asymmetric synthesis of sterically and electronically demanding linear ω-trifluoromethyl containing amino acids via alkylation of chiral equivalents of nucleophilic glycine and alanine.

Wang J, Lin D, Zhou S, Ding X, Soloshonok VA, Liu H. Wang J, et al. Among authors: lin d. J Org Chem. 2011 Jan 21;76(2):684-7. doi: 10.1021/jo102031b. Epub 2010 Dec 23. J Org Chem. 2011. PMID: 21182272

4

Synthesis of polysubstituted β-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized β-alanine derived dienes.

Ding X, Wang H, Wang J, Wang S, Lin D, Lv L, Zhou Y, Luo X, Jiang H, Aceña JL, Soloshonok VA, Liu H. Ding X, et al. Among authors: lin d. Amino Acids. 2013 Feb;44(2):791-6. doi: 10.1007/s00726-012-1404-x. Epub 2012 Sep 30. Amino Acids. 2013. PMID: 23053018

5

Enantioselective synthesis of 2-substitued-tetrahydroisoquinolin-1-yl glycine derivatives via oxidative cross-dehydrogenative coupling of tertiary amines and chiral nickel(II) glycinate.

Zhou S, Wang J, Lin D, Zhao F, Liu H. Zhou S, et al. Among authors: lin d. J Org Chem. 2013 Nov 15;78(22):11204-12. doi: 10.1021/jo401510b. Epub 2013 Oct 28. J Org Chem. 2013. PMID: 24111642

6

Highly diastereo- and enantioselective synthesis of syn-β-substituted tryptophans via asymmetric Michael addition of a chiral equivalent of nucleophilic glycine and sulfonylindoles.

Wang J, Zhou S, Lin D, Ding X, Jiang H, Liu H. Wang J, et al. Among authors: lin d. Chem Commun (Camb). 2011 Aug 7;47(29):8355-7. doi: 10.1039/c1cc12619a. Epub 2011 Jun 21. Chem Commun (Camb). 2011. PMID: 21695312

7

Highly diastereoselective synthesis of 3-indolylglycines via an asymmetric oxidative heterocoupling reaction of a chiral nickel(II) complex and indoles.

Lin D, Wang J, Zhang X, Zhou S, Lian J, Jiang H, Liu H. Lin D, et al. Chem Commun (Camb). 2013 Mar 28;49(25):2575-7. doi: 10.1039/c3cc38908a. Chem Commun (Camb). 2013. PMID: 23423386

8

Improved synthesis of rupintrivir.

Lin D, Qian W, Hilgenfeld R, Jiang H, Chen K, Liu H. Lin D, et al. Sci China Chem. 2012;55(6):1101-1107. doi: 10.1007/s11426-011-4478-5. Epub 2012 Jan 4. Sci China Chem. 2012. PMID: 32215000 Free PMC article.

9

Enterovirus 71 and coxsackievirus A16 3C proteases: binding to rupintrivir and their substrates and anti-hand, foot, and mouth disease virus drug design.

Lu G, Qi J, Chen Z, Xu X, Gao F, Lin D, Qian W, Liu H, Jiang H, Yan J, Gao GF. Lu G, et al. Among authors: lin d. J Virol. 2011 Oct;85(19):10319-31. doi: 10.1128/JVI.00787-11. Epub 2011 Jul 27. J Virol. 2011. PMID: 21795339 Free PMC article.

10

α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment.

Zhang L, Lin D, Kusov Y, Nian Y, Ma Q, Wang J, von Brunn A, Leyssen P, Lanko K, Neyts J, de Wilde A, Snijder EJ, Liu H, Hilgenfeld R. Zhang L, et al. Among authors: lin d. J Med Chem. 2020 May 14;63(9):4562-4578. doi: 10.1021/acs.jmedchem.9b01828. Epub 2020 Feb 24. J Med Chem. 2020. PMID: 32045235

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