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Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model.
Heim C, Bernhardt W, Jalilova S, Wang Z, Motsch B, Ramsperger-Gleixner M, Burzlaff N, Weyand M, Eckardt KU, Ensminger SM. Heim C, et al. Interact Cardiovasc Thorac Surg. 2016 May;22(5):561-70. doi: 10.1093/icvts/ivv352. Epub 2016 Jan 27. Interact Cardiovasc Thorac Surg. 2016. PMID: 26819270 Free PMC article.
Organ protection by hypoxia and hypoxia-inducible factors.
Bernhardt WM, Warnecke C, Willam C, Tanaka T, Wiesener MS, Eckardt KU. Bernhardt WM, et al. Methods Enzymol. 2007;435:221-45. doi: 10.1016/S0076-6879(07)35012-X. Methods Enzymol. 2007. PMID: 17998057 Review.
HIF activation protects from acute kidney injury.
Weidemann A, Bernhardt WM, Klanke B, Daniel C, Buchholz B, Câmpean V, Amann K, Warnecke C, Wiesener MS, Eckardt KU, Willam C. Weidemann A, et al. Among authors: bernhardt wm. J Am Soc Nephrol. 2008 Mar;19(3):486-94. doi: 10.1681/ASN.2007040419. Epub 2008 Feb 6. J Am Soc Nephrol. 2008. PMID: 18256363 Free PMC article.
The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis.
Buchholz B, Klanke B, Schley G, Bollag G, Tsai J, Kroening S, Yoshihara D, Wallace DP, Kraenzlin B, Gretz N, Hirth P, Eckardt KU, Bernhardt WM. Buchholz B, et al. Among authors: bernhardt wm. Nephrol Dial Transplant. 2011 Nov;26(11):3458-65. doi: 10.1093/ndt/gfr432. Epub 2011 Jul 29. Nephrol Dial Transplant. 2011. PMID: 21804086 Free PMC article.
40 results