Schuringa JJ - Search Results

1

Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML.

de Jonge HJ, Woolthuis CM, Vos AZ, Mulder A, van den Berg E, Kluin PM, van der Weide K, de Bont ES, Huls G, Vellenga E, Schuringa JJ. de Jonge HJ, et al. Among authors: schuringa jj. Leukemia. 2011 Dec;25(12):1825-33. doi: 10.1038/leu.2011.172. Epub 2011 Jul 15. Leukemia. 2011. PMID: 21760593 Clinical Trial.

2

Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components.

Schuringa JJ, Jonk LJ, Dokter WH, Vellenga E, Kruijer W. Schuringa JJ, et al. Biochem J. 2000 Apr 1;347 Pt 1(Pt 1):89-96. Biochem J. 2000. PMID: 10727406 Free PMC article.

3

Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6.

Schuringa JJ, Wierenga AT, Kruijer W, Vellenga E. Schuringa JJ, et al. Blood. 2000 Jun 15;95(12):3765-70. Blood. 2000. PMID: 10845908 Free article.

4

Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation.

Schuringa JJ, Schepers H, Vellenga E, Kruijer W. Schuringa JJ, et al. FEBS Lett. 2001 Apr 20;495(1-2):71-6. doi: 10.1016/s0014-5793(01)02354-7. FEBS Lett. 2001. PMID: 11322950 Free article.

5

Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation.

Schuringa JJ, Dekker LV, Vellenga E, Kruijer W. Schuringa JJ, et al. J Biol Chem. 2001 Jul 20;276(29):27709-15. doi: 10.1074/jbc.M009821200. Epub 2001 May 2. J Biol Chem. 2001. PMID: 11335711 Free article.

6

c-Jun and c-Fos cooperate with STAT3 in IL-6-induced transactivation of the IL-6 respone element (IRE).

Schuringa JJ, Timmer H, Luttickhuizen D, Vellenga E, Kruijer W. Schuringa JJ, et al. Cytokine. 2001 Apr 21;14(2):78-87. doi: 10.1006/cyto.2001.0856. Cytokine. 2001. PMID: 11356008

7

MEN2A-RET-induced cellular transformation by activation of STAT3.

Schuringa JJ, Wojtachnio K, Hagens W, Vellenga E, Buys CH, Hofstra R, Kruijer W. Schuringa JJ, et al. Oncogene. 2001 Aug 30;20(38):5350-8. doi: 10.1038/sj.onc.1204715. Oncogene. 2001. PMID: 11536047

8

LIF-induced STAT3 signaling in murine versus human embryonal carcinoma (EC) cells.

Schuringa JJ, van der Schaaf S, Vellenga E, Eggen BJ, Kruijer W. Schuringa JJ, et al. Exp Cell Res. 2002 Mar 10;274(1):119-29. doi: 10.1006/excr.2001.5454. Exp Cell Res. 2002. PMID: 11855863 Free article.

9

Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta1 is mediated by caspase-dependent and -independent processes.

Wierenga AT, Schuringa JJ, Eggen BJ, Kruijer W, Vellenga E. Wierenga AT, et al. Among authors: schuringa jj. Leukemia. 2002 Apr;16(4):675-82. doi: 10.1038/sj.leu.2402425. Leukemia. 2002. PMID: 11960349

10

Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3.

Benus GF, Wierenga AT, de Gorter DJ, Schuringa JJ, van Bennekum AM, Drenth-Diephuis L, Vellenga E, Eggen BJ. Benus GF, et al. Among authors: schuringa jj. Mol Biol Cell. 2005 Aug;16(8):3501-10. doi: 10.1091/mbc.e04-11-1033. Epub 2005 May 25. Mol Biol Cell. 2005. PMID: 15917296 Free PMC article.

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