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Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
Kamadurai HB, Qiu Y, Deng A, Harrison JS, Macdonald C, Actis M, Rodrigues P, Miller DJ, Souphron J, Lewis SM, Kurinov I, Fujii N, Hammel M, Piper R, Kuhlman B, Schulman BA. Kamadurai HB, et al. Among authors: kurinov i. Elife. 2013 Aug 8;2:e00828. doi: 10.7554/eLife.00828. Elife. 2013. PMID: 23936628 Free PMC article.
Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.
Brown NG, Watson ER, Weissmann F, Jarvis MA, VanderLinden R, Grace CRR, Frye JJ, Qiao R, Dube P, Petzold G, Cho SE, Alsharif O, Bao J, Davidson IF, Zheng JJ, Nourse A, Kurinov I, Peters JM, Stark H, Schulman BA. Brown NG, et al. Among authors: kurinov i. Mol Cell. 2014 Oct 23;56(2):246-260. doi: 10.1016/j.molcel.2014.09.009. Epub 2014 Oct 9. Mol Cell. 2014. PMID: 25306923 Free PMC article.
Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.
Gorelik M, Orlicky S, Sartori MA, Tang X, Marcon E, Kurinov I, Greenblatt JF, Tyers M, Moffat J, Sicheri F, Sidhu SS. Gorelik M, et al. Among authors: kurinov i. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3527-32. doi: 10.1073/pnas.1519389113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976582 Free PMC article.
73 results