Mitchell DA - Search Results

1

Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.

Mitchell DA, Cui X, Schmittling RJ, Sanchez-Perez L, Snyder DJ, Congdon KL, Archer GE, Desjardins A, Friedman AH, Friedman HS, Herndon JE 2nd, McLendon RE, Reardon DA, Vredenburgh JJ, Bigner DD, Sampson JH. Mitchell DA, et al. Blood. 2011 Sep 15;118(11):3003-12. doi: 10.1182/blood-2011-02-334565. Epub 2011 Jul 18. Blood. 2011. PMID: 21768296 Free PMC article. Clinical Trial.

2

The history, evolution, and clinical use of dendritic cell-based immunization strategies in the therapy of brain tumors.

Fecci PE, Mitchell DA, Archer GE, Morse MA, Lyerly HK, Bigner DD, Sampson JH. Fecci PE, et al. Among authors: mitchell da. J Neurooncol. 2003 Aug-Sep;64(1-2):161-76. doi: 10.1007/BF02700031. J Neurooncol. 2003. PMID: 12952297 Review.

3

Adoptive immunotherapy for malignant glioma.

Mitchell DA, Fecci PE, Sampson JH. Mitchell DA, et al. Cancer J. 2003 May-Jun;9(3):157-66. doi: 10.1097/00130404-200305000-00004. Cancer J. 2003. PMID: 12952301 Review.

4

Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.

Fecci PE, Mitchell DA, Whitesides JF, Xie W, Friedman AH, Archer GE, Herndon JE 2nd, Bigner DD, Dranoff G, Sampson JH. Fecci PE, et al. Among authors: mitchell da. Cancer Res. 2006 Mar 15;66(6):3294-302. doi: 10.1158/0008-5472.CAN-05-3773. Cancer Res. 2006. PMID: 16540683

5

Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells.

Fecci PE, Sweeney AE, Grossi PM, Nair SK, Learn CA, Mitchell DA, Cui X, Cummings TJ, Bigner DD, Gilboa E, Sampson JH. Fecci PE, et al. Among authors: mitchell da. Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4294-305. doi: 10.1158/1078-0432.CCR-06-0053. Clin Cancer Res. 2006. PMID: 16857805

6

Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.

Learn CA, Grossi PM, Schmittling RJ, Xie W, Mitchell DA, Karikari I, Wei Z, Dressman H, Sampson JH. Learn CA, et al. Among authors: mitchell da. J Neuroimmunol. 2007 Jan;182(1-2):63-72. doi: 10.1016/j.jneuroim.2006.09.016. Epub 2006 Nov 29. J Neuroimmunol. 2007. PMID: 17137636 Free PMC article.

7

Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers.

Learn CA, Fecci PE, Schmittling RJ, Xie W, Karikari I, Mitchell DA, Archer GE, Wei Z, Dressman H, Sampson JH. Learn CA, et al. Among authors: mitchell da. Clin Cancer Res. 2006 Dec 15;12(24):7306-15. doi: 10.1158/1078-0432.CCR-06-1727. Clin Cancer Res. 2006. PMID: 17189402

8

Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function.

Fecci PE, Ochiai H, Mitchell DA, Grossi PM, Sweeney AE, Archer GE, Cummings T, Allison JP, Bigner DD, Sampson JH. Fecci PE, et al. Among authors: mitchell da. Clin Cancer Res. 2007 Apr 1;13(7):2158-67. doi: 10.1158/1078-0432.CCR-06-2070. Clin Cancer Res. 2007. PMID: 17404100

9

EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells.

Ochiai H, Archer GE, Herndon JE 2nd, Kuan CT, Mitchell DA, Bigner DD, Pastan IH, Sampson JH. Ochiai H, et al. Among authors: mitchell da. Cancer Immunol Immunother. 2008 Jan;57(1):115-21. doi: 10.1007/s00262-007-0363-7. Epub 2007 Jul 19. Cancer Immunol Immunother. 2008. PMID: 17634939 Free PMC article.

10

Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma.

Mitchell DA, Xie W, Schmittling R, Learn C, Friedman A, McLendon RE, Sampson JH. Mitchell DA, et al. Neuro Oncol. 2008 Feb;10(1):10-8. doi: 10.1215/15228517-2007-035. Epub 2007 Oct 19. Neuro Oncol. 2008. PMID: 17951512 Free PMC article.

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