Irwin ME - Search Results

1

Src family kinases mediate epidermal growth factor receptor signaling from lipid rafts in breast cancer cells.

Irwin ME, Bohin N, Boerner JL. Irwin ME, et al. Cancer Biol Ther. 2011 Oct 15;12(8):718-26. doi: 10.4161/cbt.12.8.16907. Epub 2011 Oct 15. Cancer Biol Ther. 2011. PMID: 21775822 Free PMC article.

2

Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.

Irwin ME, Mueller KL, Bohin N, Ge Y, Boerner JL. Irwin ME, et al. J Cell Physiol. 2011 Sep;226(9):2316-28. doi: 10.1002/jcp.22570. J Cell Physiol. 2011. PMID: 21660955 Free PMC article.

3

Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia.

Singh MM, Irwin ME, Gao Y, Ban K, Shi P, Arlinghaus RB, Amin HM, Chandra J. Singh MM, et al. Among authors: irwin me. Cancer. 2012 Jul 1;118(13):3433-45. doi: 10.1002/cncr.26621. Epub 2011 Dec 2. Cancer. 2012. PMID: 22139798 Free PMC article.

4

Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia.

Irwin ME, Nelson LD, Santiago-O'Farrill JM, Knouse PD, Miller CP, Palla SL, Siwak DR, Mills GB, Estrov Z, Li S, Kornblau SM, Hughes DP, Chandra J. Irwin ME, et al. PLoS One. 2013 Aug 1;8(8):e70608. doi: 10.1371/journal.pone.0070608. Print 2013. PLoS One. 2013. PMID: 23936456 Free PMC article.

5

A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies.

Irwin ME, Johnson BP, Manshouri R, Amin HM, Chandra J. Irwin ME, et al. Oncotarget. 2015 Sep 15;6(27):23631-46. doi: 10.18632/oncotarget.4604. Oncotarget. 2015. PMID: 26136341 Free PMC article.

6

Expression and activity of Fyn mediate proliferation and blastic features of chronic myelogenous leukemia.

Singh MM, Howard A, Irwin ME, Gao Y, Lu X, Multani A, Chandra J. Singh MM, et al. Among authors: irwin me. PLoS One. 2012;7(12):e51611. doi: 10.1371/journal.pone.0051611. Epub 2012 Dec 17. PLoS One. 2012. PMID: 23284724 Free PMC article.

7

Combinatorial effects of histone deacetylase inhibitors (HDACi), vorinostat and entinostat, and adaphostin are characterized by distinct redox alterations.

Rivera-Del Valle N, Cheng T, Irwin ME, Donnella H, Singh MM, Chandra J. Rivera-Del Valle N, et al. Among authors: irwin me. Cancer Chemother Pharmacol. 2018 Mar;81(3):483-495. doi: 10.1007/s00280-017-3509-0. Epub 2018 Jan 8. Cancer Chemother Pharmacol. 2018. PMID: 29313067 Free PMC article.

8

Redox control of leukemia: from molecular mechanisms to therapeutic opportunities.

Irwin ME, Rivera-Del Valle N, Chandra J. Irwin ME, et al. Antioxid Redox Signal. 2013 Apr 10;18(11):1349-83. doi: 10.1089/ars.2011.4258. Epub 2012 Sep 28. Antioxid Redox Signal. 2013. PMID: 22900756 Free PMC article. Review.

9

Targeting the NRF2/HO-1 Antioxidant Pathway in FLT3-ITD-Positive AML Enhances Therapy Efficacy.

Kannan S, Irwin ME, Herbrich SM, Cheng T, Patterson LL, Aitken MJL, Bhalla K, You MJ, Konopleva M, Zweidler-McKay PA, Chandra J. Kannan S, et al. Among authors: irwin me. Antioxidants (Basel). 2022 Apr 5;11(4):717. doi: 10.3390/antiox11040717. Antioxidants (Basel). 2022. PMID: 35453402 Free PMC article.

10

The significance of low titer serum cryptococcal antigen testing from 2017 to 2023 performed in a tertiary care center.

Myint T, Wilson JR, Bhatt M, Irwin ME, Ribes JA. Myint T, et al. Among authors: irwin me. Med Mycol. 2024 Sep 6;62(9):myae093. doi: 10.1093/mmy/myae093. Med Mycol. 2024. PMID: 39237463

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