Scharenberg AM - Search Results

1

Tapping natural reservoirs of homing endonucleases for targeted gene modification.

Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL. Takeuchi R, et al. Among authors: scharenberg am. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13077-82. doi: 10.1073/pnas.1107719108. Epub 2011 Jul 22. Proc Natl Acad Sci U S A. 2011. PMID: 21784983 Free PMC article.

2

Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation.

Takeuchi R, Certo M, Caprara MG, Scharenberg AM, Stoddard BL. Takeuchi R, et al. Among authors: scharenberg am. Nucleic Acids Res. 2009 Feb;37(3):877-90. doi: 10.1093/nar/gkn1007. Epub 2008 Dec 22. Nucleic Acids Res. 2009. PMID: 19103658 Free PMC article.

3

Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.

Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL, Scharenberg AM. Baxter S, et al. Among authors: scharenberg am. Nucleic Acids Res. 2012 Sep;40(16):7985-8000. doi: 10.1093/nar/gks502. Epub 2012 Jun 7. Nucleic Acids Res. 2012. PMID: 22684507 Free PMC article.

4

Engineering and flow-cytometric analysis of chimeric LAGLIDADG homing endonucleases from homologous I-OnuI-family enzymes.

Baxter SK, Scharenberg AM, Lambert AR. Baxter SK, et al. Among authors: scharenberg am. Methods Mol Biol. 2014;1123:191-221. doi: 10.1007/978-1-62703-968-0_14. Methods Mol Biol. 2014. PMID: 24510269 Free PMC article.

5

The crystal structure and mutational analysis of human NUDT9.

Shen BW, Perraud AL, Scharenberg A, Stoddard BL. Shen BW, et al. J Mol Biol. 2003 Sep 12;332(2):385-98. doi: 10.1016/s0022-2836(03)00954-9. J Mol Biol. 2003. PMID: 12948489

6

Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases.

Volná P, Jarjour J, Baxter S, Roffler SR, Monnat RJ Jr, Stoddard BL, Scharenberg AM. Volná P, et al. Among authors: scharenberg am. Nucleic Acids Res. 2007;35(8):2748-58. doi: 10.1093/nar/gkm182. Epub 2007 Apr 10. Nucleic Acids Res. 2007. PMID: 17426121 Free PMC article.

7

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.

Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM. Jarjour J, et al. Among authors: scharenberg am. Nucleic Acids Res. 2009 Nov;37(20):6871-80. doi: 10.1093/nar/gkp726. Epub 2009 Sep 8. Nucleic Acids Res. 2009. PMID: 19740766 Free PMC article.

8

Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space.

Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM. Jacoby K, et al. Among authors: scharenberg am. Nucleic Acids Res. 2012 Jun;40(11):4954-64. doi: 10.1093/nar/gkr1303. Epub 2012 Feb 14. Nucleic Acids Res. 2012. PMID: 22334611 Free PMC article.

9

Flow cytometric assays for interrogating LAGLIDADG homing endonuclease DNA-binding and cleavage properties.

Baxter SK, Lambert AR, Scharenberg AM, Jarjour J. Baxter SK, et al. Among authors: scharenberg am. Methods Mol Biol. 2013;978:45-61. doi: 10.1007/978-1-62703-293-3_4. Methods Mol Biol. 2013. PMID: 23423888 Free PMC article.

10

Homing endonuclease target determination using SELEX adapted for yeast surface display.

Jacoby K, Scharenberg AM. Jacoby K, et al. Among authors: scharenberg am. Methods Mol Biol. 2014;1123:165-90. doi: 10.1007/978-1-62703-968-0_13. Methods Mol Biol. 2014. PMID: 24510268

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