Spencer A - Search Results

1

The novel JAK inhibitor CYT387 suppresses multiple signalling pathways, prevents proliferation and induces apoptosis in phenotypically diverse myeloma cells.

Monaghan KA, Khong T, Burns CJ, Spencer A. Monaghan KA, et al. Among authors: spencer a. Leukemia. 2011 Dec;25(12):1891-9. doi: 10.1038/leu.2011.175. Epub 2011 Jul 26. Leukemia. 2011. PMID: 21788946

2

Tumour kinetics in multiple myeloma before, during, and after treatment.

Lincz LF, Crooks RL, Way SL, Granter N, Spencer A. Lincz LF, et al. Among authors: spencer a. Leuk Lymphoma. 2001 Jan;40(3-4):373-84. doi: 10.3109/10428190109057937. Leuk Lymphoma. 2001. PMID: 11426560 Clinical Trial.

3

TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy.

Lincz LF, Yeh TX, Spencer A. Lincz LF, et al. Among authors: spencer a. Leukemia. 2001 Oct;15(10):1650-7. doi: 10.1038/sj.leu.2402251. Leukemia. 2001. PMID: 11587225

4

Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma.

Baulch-Brown C, Molloy TJ, Yeh SL, Ma D, Spencer A. Baulch-Brown C, et al. Among authors: spencer a. Leuk Res. 2007 Mar;31(3):341-52. doi: 10.1016/j.leukres.2006.07.018. Epub 2006 Sep 22. Leuk Res. 2007. PMID: 16996129

5

PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells.

Sharkey J, Khong T, Spencer A. Sharkey J, et al. Among authors: spencer a. Blood. 2007 Feb 15;109(4):1712-9. doi: 10.1182/blood-2006-05-014092. Epub 2006 Oct 10. Blood. 2007. PMID: 17032922 Free article.

6

The effect of azacitidine on interleukin-6 signaling and nuclear factor-kappaB activation and its in vitro and in vivo activity against multiple myeloma.

Khong T, Sharkey J, Spencer A. Khong T, et al. Among authors: spencer a. Haematologica. 2008 Jun;93(6):860-9. doi: 10.3324/haematol.12261. Epub 2008 Apr 28. Haematologica. 2008. PMID: 18443271 Free article.

7

Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma.

Dawson MA, Opat SS, Taouk Y, Donovan M, Zammit M, Monaghan K, Horvath N, Roberts AW, Prince HM, Hertzberg M, McLean CA, Spencer A. Dawson MA, et al. Among authors: spencer a. Clin Cancer Res. 2009 Jan 15;15(2):714-22. doi: 10.1158/1078-0432.CCR-08-1022. Clin Cancer Res. 2009. PMID: 19147779

8

Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure.

Spencer A, Prince HM, Roberts AW, Prosser IW, Bradstock KF, Coyle L, Gill DS, Horvath N, Reynolds J, Kennedy N. Spencer A, et al. J Clin Oncol. 2009 Apr 10;27(11):1788-93. doi: 10.1200/JCO.2008.18.8573. Epub 2009 Mar 9. J Clin Oncol. 2009. PMID: 19273705 Clinical Trial.

9

International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100).

Giralt S, Stadtmauer EA, Harousseau JL, Palumbo A, Bensinger W, Comenzo RL, Kumar S, Munshi NC, Dispenzieri A, Kyle R, Merlini G, San Miguel J, Ludwig H, Hajek R, Jagannath S, Blade J, Lonial S, Dimopoulos MA, Einsele H, Barlogie B, Anderson KC, Gertz M, Attal M, Tosi P, Sonneveld P, Boccadoro M, Morgan G, Sezer O, Mateos MV, Cavo M, Joshua D, Turesson I, Chen W, Shimizu K, Powles R, Richardson PG, Niesvizky R, Rajkumar SV, Durie BG; IMWG. Giralt S, et al. Leukemia. 2009 Oct;23(10):1904-12. doi: 10.1038/leu.2009.127. Epub 2009 Jun 25. Leukemia. 2009. PMID: 19554029

10

Disease status at autologous stem cell transplantation and the cell of origin phenotype are important predictors of outcome in patients with neurologic (central nervous system) relapse of diffuse large B-cell lymphoma undergoing autologous stem cell transplantation.

Patil S, Spencer A, Schwarer A, Avery S, Ritchie D, Opat S, Wei A, McLean C. Patil S, et al. Among authors: spencer a. Leuk Lymphoma. 2009 Dec;50(12):1964-8. doi: 10.3109/10428190903288456. Leuk Lymphoma. 2009. PMID: 19860614

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