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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors.
Bonsignori M, Hwang KK, Chen X, Tsao CY, Morris L, Gray E, Marshall DJ, Crump JA, Kapiga SH, Sam NE, Sinangil F, Pancera M, Yongping Y, Zhang B, Zhu J, Kwong PD, O'Dell S, Mascola JR, Wu L, Nabel GJ, Phogat S, Seaman MS, Whitesides JF, Moody MA, Kelsoe G, Yang X, Sodroski J, Shaw GM, Montefiori DC, Kepler TB, Tomaras GD, Alam SM, Liao HX, Haynes BF. Bonsignori M, et al. Among authors: yang x. J Virol. 2011 Oct;85(19):9998-10009. doi: 10.1128/JVI.05045-11. Epub 2011 Jul 27. J Virol. 2011. PMID: 21795340 Free PMC article.
Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1.
Nandi A, Lavine CL, Wang P, Lipchina I, Goepfert PA, Shaw GM, Tomaras GD, Montefiori DC, Haynes BF, Easterbrook P, Robinson JE, Sodroski JG, Yang X; NIAID Center for HIV/AIDS Vaccine Immunology. Nandi A, et al. Among authors: yang x. Virology. 2010 Jan 20;396(2):339-48. doi: 10.1016/j.virol.2009.10.044. Epub 2009 Nov 17. Virology. 2010. PMID: 19922969 Free PMC article.
Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin.
Yang X, Lee J, Mahony EM, Kwong PD, Wyatt R, Sodroski J. Yang X, et al. J Virol. 2002 May;76(9):4634-42. doi: 10.1128/jvi.76.9.4634-4642.2002. J Virol. 2002. PMID: 11932429 Free PMC article.
Soluble gp140 glycoproteins composed of the uncleaved ectodomains of gp120 and gp41 form unstable, heterogeneous oligomers, but soluble gp140 trimers can be stabilized by fusion with a C-terminal, trimeric GCN4 motif (X. Yang et al., J. Virol. 74:5716-5725, 2000). T …
Soluble gp140 glycoproteins composed of the uncleaved ectodomains of gp120 and gp41 form unstable, heterogeneous oligomers, but soluble gp14 …
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