Spreafico R - Search Results

1

Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.

Correa RG, Khan PM, Askari N, Zhai D, Gerlic M, Brown B, Magnuson G, Spreafico R, Albani S, Sergienko E, Diaz PW, Roth GP, Reed JC. Correa RG, et al. Among authors: spreafico r. Chem Biol. 2011 Jul 29;18(7):825-32. doi: 10.1016/j.chembiol.2011.06.009. Chem Biol. 2011. PMID: 21802003 Free PMC article.

2

Epipolymorphisms associated with the clinical outcome of autoimmune arthritis affect CD4+ T cell activation pathways.

Spreafico R, Rossetti M, Whitaker JW, Wang W, Lovell DJ, Albani S. Spreafico R, et al. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13845-13850. doi: 10.1073/pnas.1524056113. Epub 2016 Nov 14. Proc Natl Acad Sci U S A. 2016. PMID: 27849614 Free PMC article.

3

Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region.

Rossetti M, Spreafico R, Saidin S, Chua C, Moshref M, Leong JY, Tan YK, Thumboo J, van Loosdregt J, Albani S. Rossetti M, et al. Among authors: spreafico r. J Immunol. 2015 Jan 1;194(1):113-24. doi: 10.4049/jimmunol.1401145. Epub 2014 Dec 1. J Immunol. 2015. PMID: 25452562 Free PMC article.

4

Human CD4+CD3- innate-like T cells provide a source of TNF and lymphotoxin-αβ and are elevated in rheumatoid arthritis.

Bekiaris V, Šedy JR, Rossetti M, Spreafico R, Sharma S, Rhode-Kurnow A, Ware BC, Huang N, Macauley MG, Norris PS, Albani S, Ware CF. Bekiaris V, et al. Among authors: spreafico r. J Immunol. 2013 Nov 1;191(9):4611-8. doi: 10.4049/jimmunol.1301672. Epub 2013 Sep 27. J Immunol. 2013. PMID: 24078690 Free PMC article.

5

A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples.

Spreafico R, Rossetti M, van den Broek T, Jansen NJ, Zhang H, Moshref M, Prakken B, van Loosdregt J, van Wijk F, Albani S. Spreafico R, et al. Eur J Immunol. 2014 Oct;44(10):3141-3. doi: 10.1002/eji.201444627. Epub 2014 Aug 25. Eur J Immunol. 2014. PMID: 25042685 Free article. No abstract available.

6

A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment.

Spreafico R, Rossetti M, van Loosdregt J, Wallace CA, Massa M, Magni-Manzoni S, Gattorno M, Martini A, Lovell DJ, Albani S. Spreafico R, et al. Ann Rheum Dis. 2016 Feb;75(2):459-65. doi: 10.1136/annrheumdis-2014-206226. Epub 2014 Dec 12. Ann Rheum Dis. 2016. PMID: 25498120 Free PMC article.

7

Increased autophagy in CD4⁺ T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance.

van Loosdregt J, Rossetti M, Spreafico R, Moshref M, Olmer M, Williams GW, Kumar P, Copeland D, Pischel K, Lotz M, Albani S. van Loosdregt J, et al. Among authors: spreafico r. Eur J Immunol. 2016 Dec;46(12):2862-2870. doi: 10.1002/eji.201646375. Epub 2016 Oct 5. Eur J Immunol. 2016. PMID: 27624289 Free PMC article.

8

TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis.

Rossetti M, Spreafico R, Consolaro A, Leong JY, Chua C, Massa M, Saidin S, Magni-Manzoni S, Arkachaisri T, Wallace CA, Gattorno M, Martini A, Lovell DJ, Albani S. Rossetti M, et al. Among authors: spreafico r. Ann Rheum Dis. 2017 Feb;76(2):435-441. doi: 10.1136/annrheumdis-2015-208992. Epub 2016 Jun 16. Ann Rheum Dis. 2017. PMID: 27311837 Free PMC article.

9

Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cells.

van Loosdregt J, Spreafico R, Rossetti M, Prakken BJ, Lotz M, Albani S. van Loosdregt J, et al. Among authors: spreafico r. J Allergy Clin Immunol. 2013 May;131(5):1443-6.e1. doi: 10.1016/j.jaci.2013.02.026. Epub 2013 Mar 28. J Allergy Clin Immunol. 2013. PMID: 23541328 Free PMC article.

10

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor.

Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG. Mognol GP, et al. Among authors: spreafico r. Proc Natl Acad Sci U S A. 2019 May 14;116(20):9959-9968. doi: 10.1073/pnas.1820604116. Epub 2019 Apr 24. Proc Natl Acad Sci U S A. 2019. PMID: 31019078 Free PMC article.

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