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Aminoglycoside antibiotics in the 21st century.
Becker B, Cooper MA. Becker B, et al. ACS Chem Biol. 2013 Jan 18;8(1):105-15. doi: 10.1021/cb3005116. Epub 2012 Nov 9. ACS Chem Biol. 2013. PMID: 23110460 Review.
Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells.
Huang JX, Kaeslin G, Ranall MV, Blaskovich MA, Becker B, Butler MS, Little MH, Lash LH, Cooper MA. Huang JX, et al. Among authors: becker b. Pharmacol Res Perspect. 2015 Jun;3(3):e00148. doi: 10.1002/prp2.148. Epub 2015 May 15. Pharmacol Res Perspect. 2015. PMID: 26171227 Free PMC article.
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA. Zuegg J, et al. Among authors: becker b. Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719. Nat Commun. 2015. PMID: 26194781 Free PMC article.
Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.
Gallardo-Godoy A, Muldoon C, Becker B, Elliott AG, Lash LH, Huang JX, Butler MS, Pelingon R, Kavanagh AM, Ramu S, Phetsang W, Blaskovich MA, Cooper MA. Gallardo-Godoy A, et al. Among authors: becker b. J Med Chem. 2016 Feb 11;59(3):1068-77. doi: 10.1021/acs.jmedchem.5b01593. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26734854 Free PMC article.
Structure-Function Studies of Polymyxin B Lipononapeptides.
Gallardo-Godoy A, Hansford KA, Muldoon C, Becker B, Elliott AG, Huang JX, Pelingon R, Butler MS, Blaskovich MAT, Cooper MA. Gallardo-Godoy A, et al. Among authors: becker b. Molecules. 2019 Feb 2;24(3):553. doi: 10.3390/molecules24030553. Molecules. 2019. PMID: 30717415 Free PMC article.
Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.
Velkov T, Gallardo-Godoy A, Swarbrick JD, Blaskovich MAT, Elliott AG, Han M, Thompson PE, Roberts KD, Huang JX, Becker B, Butler MS, Lash LH, Henriques ST, Nation RL, Sivanesan S, Sani MA, Separovic F, Mertens H, Bulach D, Seemann T, Owen J, Li J, Cooper MA. Velkov T, et al. Among authors: becker b. Cell Chem Biol. 2018 Apr 19;25(4):380-391.e5. doi: 10.1016/j.chembiol.2018.01.005. Epub 2018 Feb 3. Cell Chem Biol. 2018. PMID: 29396290 Free PMC article.
A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.
Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W. Thanh GL, et al. Among authors: becker b. J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919. J Org Chem. 2010. PMID: 19961235
2,159 results