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Splice variants of tissue factor promote monocyte-endothelial interactions by triggering the expression of cell adhesion molecules via integrin-mediated signaling.
Srinivasan R, Ozhegov E, van den Berg YW, Aronow BJ, Franco RS, Palascak MB, Fallon JT, Ruf W, Versteeg HH, Bogdanov VY. Srinivasan R, et al. Among authors: versteeg hh. J Thromb Haemost. 2011 Oct;9(10):2087-96. doi: 10.1111/j.1538-7836.2011.04454.x. J Thromb Haemost. 2011. PMID: 21812913 Free PMC article.
Inhibition of tissue factor signaling suppresses tumor growth.
Versteeg HH, Schaffner F, Kerver M, Petersen HH, Ahamed J, Felding-Habermann B, Takada Y, Mueller BM, Ruf W. Versteeg HH, et al. Blood. 2008 Jan 1;111(1):190-9. doi: 10.1182/blood-2007-07-101048. Epub 2007 Sep 27. Blood. 2008. PMID: 17901245 Free PMC article.
Alternatively spliced tissue factor induces angiogenesis through integrin ligation.
van den Berg YW, van den Hengel LG, Myers HR, Ayachi O, Jordanova E, Ruf W, Spek CA, Reitsma PH, Bogdanov VY, Versteeg HH. van den Berg YW, et al. Among authors: versteeg hh. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19497-502. doi: 10.1073/pnas.0905325106. Epub 2009 Oct 29. Proc Natl Acad Sci U S A. 2009. PMID: 19875693 Free PMC article.
156 results