Searfoss G - Search Results

1

Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat.

Fielden MR, Adai A, Dunn RT 2nd, Olaharski A, Searfoss G, Sina J, Aubrecht J, Boitier E, Nioi P, Auerbach S, Jacobson-Kram D, Raghavan N, Yang Y, Kincaid A, Sherlock J, Chen SJ, Car B; Predictive Safety Testing Consortium, Carcinogenicity Working Group. Fielden MR, et al. Among authors: searfoss g. Toxicol Sci. 2011 Nov;124(1):54-74. doi: 10.1093/toxsci/kfr202. Epub 2011 Aug 2. Toxicol Sci. 2011. PMID: 21813463

2

Gene expression analysis of the acute phase response using a canine microarray.

Higgins MA, Berridge BR, Mills BJ, Schultze AE, Gao H, Searfoss GH, Baker TK, Ryan TP. Higgins MA, et al. Among authors: searfoss gh. Toxicol Sci. 2003 Aug;74(2):470-84. doi: 10.1093/toxsci/kfg142. Epub 2003 May 28. Toxicol Sci. 2003. PMID: 12773757

3

Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes.

Guo Y, Jolly RA, Halstead BW, Baker TK, Stutz JP, Huffman M, Calley JN, West A, Gao H, Searfoss GH, Li S, Irizarry AR, Qian HR, Stevens JL, Ryan TP. Guo Y, et al. Among authors: searfoss gh. Toxicol Sci. 2007 Apr;96(2):294-309. doi: 10.1093/toxsci/kfm009. Epub 2007 Jan 25. Toxicol Sci. 2007. PMID: 17255113

4

The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors.

Searfoss GH, Paisley BM, Goldstein KM, Baker TK, Willy JA. Searfoss GH, et al. Toxicol Sci. 2019 Jan 1;167(1):202-210. doi: 10.1093/toxsci/kfy229. Toxicol Sci. 2019. PMID: 30215789

5

Technological Advances in Cardiovascular Safety Assessment Decrease Preclinical Animal Use and Improve Clinical Relevance.

Berridge BR, Schultze AE, Heyen JR, Searfoss GH, Sarazan RD. Berridge BR, et al. Among authors: searfoss gh. ILAR J. 2016 Dec;57(2):120-132. doi: 10.1093/ilar/ilw028. ILAR J. 2016. PMID: 28053066

6

Temporal gene expression analysis of monolayer cultured rat hepatocytes.

Baker TK, Carfagna MA, Gao H, Dow ER, Li Q, Searfoss GH, Ryan TP. Baker TK, et al. Among authors: searfoss gh. Chem Res Toxicol. 2001 Sep;14(9):1218-31. doi: 10.1021/tx015518a. Chem Res Toxicol. 2001. PMID: 11559036

7

The role of transcriptome analysis in pre-clinical toxicology.

Searfoss GH, Ryan TP, Jolly RA. Searfoss GH, et al. Curr Mol Med. 2005 Feb;5(1):53-64. doi: 10.2174/1566524053152825. Curr Mol Med. 2005. PMID: 15720270 Review.

8

Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity.

Sutherland JJ, Webster YW, Willy JA, Searfoss GH, Goldstein KM, Irizarry AR, Hall DG, Stevens JL. Sutherland JJ, et al. Among authors: searfoss gh. Pharmacogenomics J. 2018 May 22;18(3):377-390. doi: 10.1038/tpj.2017.17. Epub 2017 Apr 25. Pharmacogenomics J. 2018. PMID: 28440344

9

Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor.

Searfoss GH, Jordan WH, Calligaro DO, Galbreath EJ, Schirtzinger LM, Berridge BR, Gao H, Higgins MA, May PC, Ryan TP. Searfoss GH, et al. J Biol Chem. 2003 Nov 14;278(46):46107-16. doi: 10.1074/jbc.M307757200. Epub 2003 Aug 29. J Biol Chem. 2003. PMID: 12949072 Free article.

10

Hepatic gene expression changes in mice associated with prolonged sublethal microcystin exposure.

Clark SP, Davis MA, Ryan TP, Searfoss GH, Hooser SB. Clark SP, et al. Among authors: searfoss gh. Toxicol Pathol. 2007 Jun;35(4):594-605. doi: 10.1080/01926230701383210. Toxicol Pathol. 2007. PMID: 17654400

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