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Page 1
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. Gong GQ, et al. Among authors: vanhaesebroeck b. Nature. 2023 Jun;618(7963):159-168. doi: 10.1038/s41586-023-05972-2. Epub 2023 May 24. Nature. 2023. PMID: 37225977 Free PMC article.
Gene targeting: attention to detail.
Vanhaesebroeck B, Rohn JL, Waterfield MD. Vanhaesebroeck B, et al. Cell. 2004 Aug 6;118(3):274-6. doi: 10.1016/j.cell.2004.07.018. Cell. 2004. PMID: 15294152 Free article.
Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.
Papakonstanti EA, Zwaenepoel O, Bilancio A, Burns E, Nock GE, Houseman B, Shokat K, Ridley AJ, Vanhaesebroeck B. Papakonstanti EA, et al. Among authors: vanhaesebroeck b. J Cell Sci. 2008 Dec 15;121(Pt 24):4124-33. doi: 10.1242/jcs.032763. Epub 2008 Nov 25. J Cell Sci. 2008. PMID: 19033389
PI3K regulatory subunits lose control in cancer.
Berenjeno IM, Vanhaesebroeck B. Berenjeno IM, et al. Among authors: vanhaesebroeck b. Cancer Cell. 2009 Dec 8;16(6):449-50. doi: 10.1016/j.ccr.2009.11.017. Cancer Cell. 2009. PMID: 19962660 Free article.
The emerging mechanisms of isoform-specific PI3K signalling.
Vanhaesebroeck B, Guillermet-Guibert J, Graupera M, Bilanges B. Vanhaesebroeck B, et al. Nat Rev Mol Cell Biol. 2010 May;11(5):329-41. doi: 10.1038/nrm2882. Epub 2010 Apr 9. Nat Rev Mol Cell Biol. 2010. PMID: 20379207 Review.
Essential role of class II PI3K-C2α in platelet membrane morphology.
Valet C, Chicanne G, Severac C, Chaussade C, Whitehead MA, Cabou C, Gratacap MP, Gaits-Iacovoni F, Vanhaesebroeck B, Payrastre B, Severin S. Valet C, et al. Among authors: vanhaesebroeck b. Blood. 2015 Aug 27;126(9):1128-37. doi: 10.1182/blood-2015-03-636670. Epub 2015 Jun 24. Blood. 2015. PMID: 26109204 Free article.
Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity.
Alliouachene S, Bilanges B, Chicanne G, Anderson KE, Pearce W, Ali K, Valet C, Posor Y, Low PC, Chaussade C, Scudamore CL, Salamon RS, Backer JM, Stephens L, Hawkins PT, Payrastre B, Vanhaesebroeck B. Alliouachene S, et al. Among authors: vanhaesebroeck b. Cell Rep. 2015 Dec 1;13(9):1881-94. doi: 10.1016/j.celrep.2015.10.052. Epub 2015 Nov 19. Cell Rep. 2015. PMID: 26655903 Free PMC article.
222 results