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Page 1
Variants in Apaf-1 segregating with major depression promote apoptosome function.
Harlan J, Chen Y, Gubbins E, Mueller R, Roch JM, Walter K, Lake M, Olsen T, Metzger P, Dorwin S, Ladror U, Egan DA, Severin J, Johnson RW, Holzman TF, Voelp K, Davenport C, Beck A, Potter J, Gopalakrishnan M, Hahn A, Spear BB, Halbert DN, Sullivan JP, Abkevich V, Neff CD, Skolnick MH, Shattuck D, Katz DA. Harlan J, et al. Mol Psychiatry. 2006 Jan;11(1):76-85. doi: 10.1038/sj.mp.4001755. Mol Psychiatry. 2006. PMID: 16231040
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
Pei Z, Li X, Longenecker K, von Geldern TW, Wiedeman PE, Lubben TH, Zinker BA, Stewart K, Ballaron SJ, Stashko MA, Mika AK, Beno DW, Long M, Wells H, Kempf-Grote AJ, Madar DJ, McDermott TS, Bhagavatula L, Fickes MG, Pireh D, Solomon LR, Lake MR, Edalji R, Fry EH, Sham HL, Trevillyan JM. Pei Z, et al. Among authors: lake mr. J Med Chem. 2006 Jun 15;49(12):3520-35. doi: 10.1021/jm051283e. J Med Chem. 2006. PMID: 16759095
Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists.
Chen J, Lake MR, Sabet RS, Niforatos W, Pratt SD, Cassar SC, Xu J, Gopalakrishnan S, Pereda-Lopez A, Gopalakrishnan M, Holzman TF, Moreland RB, Walter KA, Faltynek CR, Warrior U, Scott VE. Chen J, et al. Among authors: lake mr. J Biomol Screen. 2007 Feb;12(1):61-9. doi: 10.1177/1087057106295220. Epub 2006 Nov 12. J Biomol Screen. 2007. PMID: 17099245
Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.
Sun C, Song D, Davis-Taber RA, Barrett LW, Scott VE, Richardson PL, Pereda-Lopez A, Uchic ME, Solomon LR, Lake MR, Walter KA, Hajduk PJ, Olejniczak ET. Sun C, et al. Among authors: lake mr. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7875-80. doi: 10.1073/pnas.0611397104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470806 Free PMC article.
Empowering therapeutic antibodies with IFN-α for cancer immunotherapy.
Guo J, Xiao Y, Iyer R, Lu X, Lake M, Ladror U, Harlan J, Samanta T, Tomlinson M, Bukofzer G, Donawho C, Shoemaker A, Huang TH. Guo J, et al. PLoS One. 2019 Aug 8;14(8):e0219829. doi: 10.1371/journal.pone.0219829. eCollection 2019. PLoS One. 2019. PMID: 31393905 Free PMC article.
25 results