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Page 1
Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model.
Meléndez-López SG, Herdman S, Hirata K, Choi MH, Choe Y, Craik C, Caffrey CR, Hansell E, Chávez-Munguía B, Chen YT, Roush WR, McKerrow J, Eckmann L, Guo J, Stanley SL Jr, Reed SL. Meléndez-López SG, et al. Among authors: mckerrow j. Eukaryot Cell. 2007 Jul;6(7):1130-6. doi: 10.1128/EC.00094-07. Epub 2007 May 18. Eukaryot Cell. 2007. PMID: 17513563 Free PMC article.
A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.
He C, Nora GP, Schneider EL, Kerr ID, Hansell E, Hirata K, Gonzalez D, Sajid M, Boyd SE, Hruz P, Cobo ER, Le C, Liu WT, Eckmann L, Dorrestein PC, Houpt ER, Brinen LS, Craik CS, Roush WR, McKerrow J, Reed SL. He C, et al. Among authors: mckerrow j. J Biol Chem. 2010 Jun 11;285(24):18516-27. doi: 10.1074/jbc.M109.086181. Epub 2010 Apr 8. J Biol Chem. 2010. PMID: 20378535 Free PMC article.
Lead identification to clinical candidate selection: drugs for Chagas disease.
Neitz RJ, Chen S, Supek F, Yeh V, Kellar D, Gut J, Bryant C, Gallardo-Godoy A, Molteni V, Roach SL, Khare S, Stinson M, Chatterjee AK, Robertson S, Renslo AR, Arkin M, Glynne R, McKerrow J, Siqueira-Neto JL. Neitz RJ, et al. Among authors: mckerrow j. J Biomol Screen. 2015 Jan;20(1):101-11. doi: 10.1177/1087057114553103. Epub 2014 Oct 3. J Biomol Screen. 2015. PMID: 25281737
Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs.
Akama T, Freund YR, Berry PW, Carter DS, Easom EE, Jarnagin K, Lunde CS, Plattner JJ, Rock F, Stefanakis R, Fischer C, Bulman CA, Lim KC, Suzuki BM, Tricoche N, Mansour A, DiCosty U, McCall S, Carson B, McCall JW, McKerrow J, Hübner MP, Specht S, Hoerauf A, Lustigman S, Sakanari JA, Jacobs RT. Akama T, et al. Among authors: mckerrow j. ACS Infect Dis. 2020 Feb 14;6(2):173-179. doi: 10.1021/acsinfecdis.9b00396. Epub 2020 Jan 14. ACS Infect Dis. 2020. PMID: 31876154 Free PMC article.
Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs.
Carter DS, Jacobs RT, Freund YR, Berry PW, Akama T, Easom EE, Lunde CS, Rock F, Stefanakis R, McKerrow J, Fischer C, Bulman CA, Lim KC, Suzuki BM, Tricoche N, Sakanari JA, Lustigman S, Plattner JJ. Carter DS, et al. Among authors: mckerrow j. ACS Infect Dis. 2020 Feb 14;6(2):180-185. doi: 10.1021/acsinfecdis.9b00397. Epub 2020 Jan 28. ACS Infect Dis. 2020. PMID: 31876143 Free PMC article.
391 results