Xia M - Search Results

1

SNX-2112, a novel Hsp90 inhibitor, induces G2/M cell cycle arrest and apoptosis in MCF-7 cells.

Wang SX, Ju HQ, Liu KS, Zhang JX, Wang X, Xiang YF, Wang R, Liu JY, Liu QY, Xia M, Xing GW, Liu Z, Wang YF. Wang SX, et al. Among authors: xia m. Biosci Biotechnol Biochem. 2011;75(8):1540-5. doi: 10.1271/bbb.110225. Epub 2011 Aug 7. Biosci Biotechnol Biochem. 2011. PMID: 21821931 Free article.

2

Transcriptomic and proteomic approach to studying SNX-2112-induced K562 cells apoptosis and anti-leukemia activity in K562-NOD/SCID mice.

Jin L, Xiao CL, Lu CH, Xia M, Xing GW, Xiong S, Liu QY, Liu H, Li YC, Ge F, Wang QD, He QY, Wang YF. Jin L, et al. Among authors: xia m. FEBS Lett. 2009 Jun 18;583(12):1859-66. doi: 10.1016/j.febslet.2009.04.046. Epub 2009 May 8. FEBS Lett. 2009. PMID: 19427857 Free article.

3

Determination of SNX-2112, a selective Hsp90 inhibitor, in plasma samples by high-performance liquid chromatography and its application to pharmacokinetics in rats.

Zhai QQ, Gong GQ, Luo Y, Wang QD, Xia M, Xing GW, Li YC, Jiang JH, Liu Z, Liu QY, Wang YF. Zhai QQ, et al. Among authors: xia m. J Pharm Biomed Anal. 2010 Dec 1;53(4):1048-52. doi: 10.1016/j.jpba.2010.06.031. Epub 2010 Jul 6. J Pharm Biomed Anal. 2010. PMID: 20675090

4

Synthesis and in vitro anti-HSV-1 activity of a novel Hsp90 inhibitor BJ-B11.

Ju HQ, Xiang YF, Xin BJ, Pei Y, Lu JX, Wang QL, Xia M, Qian CW, Ren Z, Wang SY, Wang YF, Xing GW. Ju HQ, et al. Among authors: xia m. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1675-7. doi: 10.1016/j.bmcl.2011.01.098. Epub 2011 Jan 27. Bioorg Med Chem Lett. 2011. PMID: 21334891

5

BJ-B11, a novel Hsp90 inhibitor, induces apoptosis in human chronic myeloid leukemia K562 cells through the mitochondria-dependent pathway.

Ju HQ, Wang SX, Xiang YF, Liu Z, Liu JY, Chen ZP, Zeng FL, Xia M, Liu ZH, Xing GW, Wang SY, Wang YF. Ju HQ, et al. Among authors: xia m. Eur J Pharmacol. 2011 Sep;666(1-3):26-34. doi: 10.1016/j.ejphar.2011.05.020. Epub 2011 May 23. Eur J Pharmacol. 2011. PMID: 21620825

6

SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cells.

Liu KS, Liu H, Qi JH, Liu QY, Liu Z, Xia M, Xing GW, Wang SX, Wang YF. Liu KS, et al. Among authors: xia m. Cancer Lett. 2012 May 28;318(2):180-8. doi: 10.1016/j.canlet.2011.12.015. Epub 2011 Dec 17. Cancer Lett. 2012. PMID: 22182451

7

Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors.

Xiang YF, Qian CW, Xing GW, Hao J, Xia M, Wang YF. Xiang YF, et al. Among authors: xia m. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4703-6. doi: 10.1016/j.bmcl.2012.05.079. Epub 2012 May 26. Bioorg Med Chem Lett. 2012. PMID: 22704890

8

The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells.

Liu KS, Zhang Y, Ding WC, Wang SX, Xiang YF, Yang P, Chen ZP, Zheng K, Liu Z, Xia M, Wang YF. Liu KS, et al. Among authors: xia m. Int J Oncol. 2012 Dec;41(6):2276-84. doi: 10.3892/ijo.2012.1670. Epub 2012 Oct 17. Int J Oncol. 2012. PMID: 23076967

9

The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways.

Wang R, Shao F, Liu Z, Zhang J, Wang S, Liu J, Liu H, Chen H, Liu K, Xia M, Wang Y. Wang R, et al. Among authors: xia m. Chem Biol Interact. 2013 Sep 5;205(1):1-10. doi: 10.1016/j.cbi.2013.06.007. Epub 2013 Jun 15. Chem Biol Interact. 2013. PMID: 23777986

10

The Hsp90 inhibitor SNX-2112 induces apoptosis of human hepatocellular carcinoma cells: the role of ER stress.

Wang X, Wang S, Liu Y, Ding W, Zheng K, Xiang Y, Liu K, Wang D, Zeng Y, Xia M, Yang D, Wang Y. Wang X, et al. Among authors: xia m. Biochem Biophys Res Commun. 2014 Mar 28;446(1):160-6. doi: 10.1016/j.bbrc.2014.02.081. Epub 2014 Feb 25. Biochem Biophys Res Commun. 2014. PMID: 24582562

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