Liu DR - Search Results

1

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.

Pattanayak V, Ramirez CL, Joung JK, Liu DR. Pattanayak V, et al. Among authors: liu dr. Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670. Nat Methods. 2011. PMID: 21822273 Free PMC article.

2

An in vivo selection system for homing endonuclease activity.

Gruen M, Chang K, Serbanescu I, Liu DR. Gruen M, et al. Among authors: liu dr. Nucleic Acids Res. 2002 Apr 1;30(7):e29. doi: 10.1093/nar/30.7.e29. Nucleic Acids Res. 2002. PMID: 11917035 Free PMC article.

3

Nucleic acid evolution and minimization by nonhomologous random recombination.

Bittker JA, Le BV, Liu DR. Bittker JA, et al. Among authors: liu dr. Nat Biotechnol. 2002 Oct;20(10):1024-9. doi: 10.1038/nbt736. Epub 2002 Sep 9. Nat Biotechnol. 2002. PMID: 12219078 Free PMC article.

4

Reaction discovery enabled by DNA-templated synthesis and in vitro selection.

Kanan MW, Rozenman MM, Sakurai K, Snyder TM, Liu DR. Kanan MW, et al. Among authors: liu dr. Nature. 2004 Sep 30;431(7008):545-9. doi: 10.1038/nature02920. Nature. 2004. PMID: 15457254 Free PMC article.

5

Directed evolution and substrate specificity profile of homing endonuclease I-SceI.

Doyon JB, Pattanayak V, Meyer CB, Liu DR. Doyon JB, et al. Among authors: liu dr. J Am Chem Soc. 2006 Feb 22;128(7):2477-84. doi: 10.1021/ja057519l. J Am Chem Soc. 2006. PMID: 16478204

6

Dissecting protein structure and function using directed evolution.

Yuen CM, Liu DR. Yuen CM, et al. Among authors: liu dr. Nat Methods. 2007 Dec;4(12):995-7. doi: 10.1038/nmeth1207-995. Nat Methods. 2007. PMID: 18049466 Free PMC article. Review.

7

An in vitro translation, selection and amplification system for peptide nucleic acids.

Brudno Y, Birnbaum ME, Kleiner RE, Liu DR. Brudno Y, et al. Among authors: liu dr. Nat Chem Biol. 2010 Feb;6(2):148-55. doi: 10.1038/nchembio.280. Epub 2009 Dec 27. Nat Chem Biol. 2010. PMID: 20081830 Free PMC article.

8

A system for the continuous directed evolution of biomolecules.

Esvelt KM, Carlson JC, Liu DR. Esvelt KM, et al. Among authors: liu dr. Nature. 2011 Apr 28;472(7344):499-503. doi: 10.1038/nature09929. Epub 2011 Apr 10. Nature. 2011. PMID: 21478873 Free PMC article.

9

Enzyme-free translation of DNA into sequence-defined synthetic polymers structurally unrelated to nucleic acids.

Niu J, Hili R, Liu DR. Niu J, et al. Among authors: liu dr. Nat Chem. 2013 Apr;5(4):282-92. doi: 10.1038/nchem.1577. Epub 2013 Mar 3. Nat Chem. 2013. PMID: 23511416 Free PMC article.

10

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.

Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. Pattanayak V, et al. Among authors: liu dr. Nat Biotechnol. 2013 Sep;31(9):839-43. doi: 10.1038/nbt.2673. Epub 2013 Aug 11. Nat Biotechnol. 2013. PMID: 23934178 Free PMC article.

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