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Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect.
Kögl T, Chang HF, Staniek J, Chiang SCC, Thoulass G, Lao J, Weißert K, Dettmer-Monaco V, Geiger K, Manna PT, Beziat V, Momenilandi M, Tu SM, Keppler SJ, Pattu V, Wolf P, Kupferschmid L, Tholen S, Covill LE, Ebert K, Straub T, Groß M, Gather R, Engel H, Salzer U, Schell C, Maier S, Lehmberg K, Cornu TI, Pircher H, Shahrooei M, Parvaneh N, Elling R, Rizzi M, Bryceson YT, Ehl S, Aichele P, Ammann S. Kögl T, et al. Among authors: keppler sj. J Exp Med. 2024 Jul 1;221(7):e20221122. doi: 10.1084/jem.20221122. Epub 2024 May 9. J Exp Med. 2024. PMID: 38722309 Free PMC article.
B cell-mediated CD4 T-cell costimulation via CD86 exacerbates pro-inflammatory cytokine production during autoimmune intestinal inflammation.
Gadjalova I, Heinze JM, Goess MC, Hofmann J, Buck A, Weber MC, Blissenbach B, Kampick M, Krut O, Steiger K, Janssen KP, Neumann PA, Ruland J, Keppler SJ. Gadjalova I, et al. Among authors: keppler sj. Mucosal Immunol. 2024 Feb;17(1):67-80. doi: 10.1016/j.mucimm.2023.10.005. Epub 2023 Oct 31. Mucosal Immunol. 2024. PMID: 37918715 Free article.
The Small Rho GTPase TC10 Modulates B Cell Immune Responses.
Burbage M, Keppler SJ, Montaner B, Mattila PK, Batista FD. Burbage M, et al. Among authors: keppler sj. J Immunol. 2017 Sep 1;199(5):1682-1695. doi: 10.4049/jimmunol.1602167. Epub 2017 Jul 26. J Immunol. 2017. PMID: 28747344 Free PMC article.
Nck adaptor proteins modulate differentiation and effector function of T cells.
Lu KH, Keppler S, Leithäuser F, Mattfeldt T, Castello A, Kostezka U, Küblbeck G, Schmitt S, Klevenz A, Prokosch S, Pougialis G, Pawson T, Batista F, Tafuri A, Arnold B. Lu KH, et al. J Leukoc Biol. 2015 Sep;98(3):301-11. doi: 10.1189/jlb.1HI1114-565R. Epub 2015 May 20. J Leukoc Biol. 2015. PMID: 25995205
28 results