Xia M - Search Results

1

Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors.

Huang W, Huang R, Attene-Ramos MS, Sakamuru S, Englund EE, Inglese J, Austin CP, Xia M. Huang W, et al. Among authors: xia m. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5239-43. doi: 10.1016/j.bmcl.2011.07.043. Epub 2011 Jul 21. Bioorg Med Chem Lett. 2011. PMID: 21831635 Free PMC article.

2

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Among authors: xia m. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

3

Identification of a potent new chemotype for the selective inhibition of PDE4.

Skoumbourdis AP, Huang R, Southall N, Leister W, Guo V, Cho MH, Inglese J, Nirenberg M, Austin CP, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: xia m. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1297-303. doi: 10.1016/j.bmcl.2008.01.028. Epub 2008 Jan 11. Bioorg Med Chem Lett. 2008. PMID: 18243697 Free PMC article.

4

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening.

Huang R, Southall N, Cho MH, Xia M, Inglese J, Austin CP. Huang R, et al. Among authors: xia m. Chem Res Toxicol. 2008 Mar;21(3):659-67. doi: 10.1021/tx700365e. Epub 2008 Feb 19. Chem Res Toxicol. 2008. PMID: 18281954 Free PMC article.

5

Compound cytotoxicity profiling using quantitative high-throughput screening.

Xia M, Huang R, Witt KL, Southall N, Fostel J, Cho MH, Jadhav A, Smith CS, Inglese J, Portier CJ, Tice RR, Austin CP. Xia M, et al. Environ Health Perspect. 2008 Mar;116(3):284-91. doi: 10.1289/ehp.10727. Environ Health Perspect. 2008. PMID: 18335092 Free PMC article.

6

A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker.

Cho MH, Niles A, Huang R, Inglese J, Austin CP, Riss T, Xia M. Cho MH, et al. Among authors: xia m. Toxicol In Vitro. 2008 Jun;22(4):1099-106. doi: 10.1016/j.tiv.2008.02.013. Epub 2008 Mar 4. Toxicol In Vitro. 2008. PMID: 18400464 Free PMC article.

7

Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory.

Xia M, Huang R, Guo V, Southall N, Cho MH, Inglese J, Austin CP, Nirenberg M. Xia M, et al. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2412-7. doi: 10.1073/pnas.0813020106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196967 Free PMC article.

8

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.

Skoumbourdis AP, Leclair CA, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin CP, Michnick SW, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: xia m. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92. doi: 10.1016/j.bmcl.2009.01.057. Epub 2009 Jan 23. Bioorg Med Chem Lett. 2009. PMID: 19464886 Free PMC article.

9

Identification of chemical compounds that induce HIF-1alpha activity.

Xia M, Huang R, Sun Y, Semenza GL, Aldred SF, Witt KL, Inglese J, Tice RR, Austin CP. Xia M, et al. Toxicol Sci. 2009 Nov;112(1):153-63. doi: 10.1093/toxsci/kfp123. Epub 2009 Jun 5. Toxicol Sci. 2009. PMID: 19502547 Free PMC article.

10

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel.

Titus SA, Beacham D, Shahane SA, Southall N, Xia M, Huang R, Hooten E, Zhao Y, Shou L, Austin CP, Zheng W. Titus SA, et al. Among authors: xia m. Anal Biochem. 2009 Nov 1;394(1):30-8. doi: 10.1016/j.ab.2009.07.003. Epub 2009 Jul 5. Anal Biochem. 2009. PMID: 19583963 Free PMC article.

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